Listar QFA_Articles por fuente "PNAS, October 9, 2018, vol. 115, no. 41"
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Parallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational tools
National Academy of Sciences (2018)Thymidylate synthase was one of the most studied enzymes due to its critical role in molecular pathogenesis of cancer. Nevertheless, many atomistic details of its chemical mechanism remain unknown or debated, thereby ...