Visualitza QFA_Articles per autoria "6ac3004e-12c4-4767-91fd-bab521dbf653"
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Characterization of a recently detected halogenated aminorex derivative: para-fluoro-4-methylaminorex (4′F-4-MAR)
Fabregat-Safont, David; Carbón, X.; Ventura, Mireia; Fornís, I.; Hernandez, Felix; Ibáñez, Maria Nature Research (2019)Despite the fact that 33% of the new psychoactive substances seized in 2015 were synthetic cathinones, the number of these derivatives has been decreasing in the last years, probably as a consequence of the unfavourable ... -
Improving Target and Suspect Screening High-Resolution Mass Spectrometry Workflows in Environmental Analysis by Ion Mobility Separation
Celma, Alberto; Sancho, Juan V; Schymanski, Emma; Fabregat-Safont, David; Ibáñez, Maria; Goshawk, Jeff; Barknowitz, Gitte; Hernandez, Felix; Bijlsma, Lubertus American Chemical Society (2020-11-19)Currently, the most powerful approach to monitor organic micropollutants (OMPs) in environmental samples is the combination of target, suspect, and nontarget screening strategies using high-resolution mass spectrometry ... -
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Costa-Machado, Luis Filipe; García-Domínguez, Esther; McIntyre, Rebecca L.; Lopez Aceituno, Jose Luis; Ballesteros-González, Álvaro; Tapia-Gonzalez, Andrea; Fabregat-Safont, David; Eisenberg, Tobias; Gómez, Jesús; Plaza, Adrian; Sierra Ramírez, Arantzazu; Pérez, Manuel; Villanueva Bermejo, David; Fornari, Tiziana; Loza García, María Isabel; Herradón, Gonzalo; Hofer, Sebastian; Magnes, Christoph; Madeo, Frank; Duerr, Janet S.; Pozo, Oscar; Galindo, Máximo Ibo; del Pino, Isabel; Houtkooper, Riekelt H.; Megias, Diego; Viña, José; Gomez-Cabrera , Mari Carmen; Fernandez-Marcos, Pablo J. Nature Research (2023)Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show ... -
Present and future of metabolic and metabolomics studies focused on classical psychedelics in humans
Madrid-Gambin, Francisco; Fabregat-Safont, David; Gomez-Gomez, Alex; Olesti, Eulàlia; Mason, Natasha; Ramaekers, Johannes; Pozo, Oscar Elsevier (2023-12-31)Psychedelics are classical hallucinogen drugs that induce a marked altered state of consciousness. In recent years, there has been renewed attention to the possible use of classical psychedelics for the treatment of certain ... -
Updating the list of known opioids through identification and characterization of the new opioid derivative 3,4-dichloro-N- (2-(diethylamino)cyclohexyl)-N- methylbenzamide (U-49900)
Fabregat-Safont, David; Carbón, X.; Ventura, Mireia; Fornís, I.; Guillamón, Eva; Sancho, Juan V; Hernandez, Felix; Ibáñez, Maria Springer Nature (2017)New psychoactive substances have been rapidly growing in popularity in the drug market as non-illegal drugs. In the last few years, an increment has been reported on the use of synthetic alternatives to heroin, the synthetic ...