ListarPSB_Articles por tema "Locomotor stimulation"
Mostrando ítems 1-4 de 4
-
Alpha-lipoic acid, a scavenging agent for H2O2, reduces ethanol-stimulated locomotion in mice
Springer-Verlag (2011-07-19)Rationale The main system of central ethanol oxidation is mediated by the enzyme catalase. By reacting with H2O2, brain catalase forms compound I (the catalase–H2O2 system), which is able to oxidize ethanol to acetaldehyde ... -
Participation of L-type calcium channels in ethanol-induced behavioral stimulation and motor incoordination: Effects of diltiazem and verapamil
Elsevier (2010-06)Calcium flux through voltage gate calcium channels (VGCC) is involved in many neuronal processes such as membrane depolarization, gene expression, hormone secretion, and neurotransmitter release. Several studies have shown ... -
The H2O2 scavenger ebselen decreases ethanol-induced locomotor stimulation in mice
Elsevier (2012)Background In the brain, the enzyme catalase by reacting with H2O2 forms Compound I (catalase–H2O2 system), which is the main system of central ethanol metabolism to acetaldehyde. Previous research has demonstrated that ... -
The MAO-A inhibitor clorgyline reduces ethanol-induced locomotion and its volitional intake in mice
Elsevier (2014)Hydrogen peroxide is the co-substrate used by the enzyme catalase to form Compound I (the catalase–H2O2 system), which is the major pathway for the conversion of ethanol (EtOH) into acetaldehyde in the brain. This acetaldehyde ...