• openAccess   A Working Hypothesis for the Role of the Cerebellum in Impulsivity and Compulsivity 

      MIQUEL, MARTA; Nicola, Saleem; Gil-Miravet, Isis; Guarque-Chabrera, Julian; Sanchez-Hernandez, Aitor Frontiers Media (2019-05)
      Growing evidence associates cerebellar abnormalities with several neuropsychiatric disorders in which compulsive symptomatology and impulsivity are part of the disease pattern. Symptomatology of autism, addiction, ...
    • closedAccess   Cerebellar perineuronal nets in cocaine-induced pavlovian memory: Site matters 

      Carbó Gas, María; Moreno Rius, Josep; Guarque-Chabrera, Julian; Vázquez Sanromán, Dolores; Gil-Miravet, Isis; Carulli, Daniela; Hoebeek, Freek; De Zeeuw, Chris; Sanchis-Segura, Carla; MIQUEL, MARTA Elsevier (2017-07-14)
      One of the key mechanisms for the stabilization of synaptic changes near the end of critical periods for experience-dependent plasticity is the formation of specific lattice extracellular matrix structures called perineuronal ...
    • openAccess   Cocaine-Induced Preference Conditioning: a Machine Vision Perspective 

      Traver Roig, Vicente Javier; Pla, Filiberto; MIQUEL, MARTA; Carbó Gas, María; Gil-Miravet, Isis; Guarque-Chabrera, Julian Springer (2018)
      Existing work on drug-induced synaptic changes has shown that the expression of perineuronal nets (PNNs) at the cerebellar cortex can be regulated by cocaine-related memory. However, these studies on animals have mostly ...
    • openAccess   Neural correlates of cocaine-induced conditioned place preference in the posterior cerebellar cortex 

      Rodríguez Borillo, Olga; Roselló-Jiménez, Lorena; Guarque-Chabrera, Julian; Palau-Batet, María; Gil-Miravet, Isis; Pastor Medall, Raúl; MIQUEL, MARTA; Font Hurtado, Laura Frontiers Media (2023)
      Introduction: Addictive drugs are potent neuropharmacological agents capable of inducing long-lasting changes in learning and memory neurocircuitry. With repeated use, contexts and cues associated with consumption can ...
    • openAccess   Role of Perineuronal nets in the cerebellar cortex in cocaine-induced conditioned preference, extinction, and reinstatement 

      Guarque-Chabrera, Julian; Sanchez-Hernandez, Aitor; Ibáñez-Marín, Patricia; Melchor Eixea, Ignasi; MIQUEL, MARTA Elsevier Ltd (2022-08-17)
      Perineuronal nets (PNNs) are cartilage-like structures of extracellular matrix molecules that enwrap in a net-like manner the cell-body and proximal dendrites of special subsets of neurons. PNNs stabilize their incoming ...
    • openAccess   The Cerebellum on Cocaine 

      MIQUEL, MARTA; Gil-Miravet, Isis; Guarque-Chabrera, Julian Frontiers Media (2020-10-21)
      The traditional cerebellum’s role has been linked to the high computational demands for sensorimotor control. However, several findings have pointed to its involvement in executive and emotional functions in the last ...
    • openAccess   The role of the cerebellum in drug-cue associative memory: functional interactions with the medial prefrontal cortex 

      Gil-Miravet, Isis; Guarque-Chabrera, Julian; Carbó Gas, María; Olucha-Bordonau, Francisco E; MIQUEL, MARTA John Wiley (2018-10-02)
      Drug-induced Pavlovian memories are thought to be crucial for drug addiction because they guide behaviour towards environments with drug availability. Drug-related memory depends on persistent changes in dopamine-glutamate ...
    • openAccess   Time-dependent regulation of perineuronal nets in the cerebellar cortex during abstinence of cocaine-self administration 

      Sanchez-Hernandez, Aitor; Nicolas, Celine; Gil-Miravet, Isis; Guarque-Chabrera, Julian; Solinas, Marcello; MIQUEL, MARTA Springer (2021-01-03)
      Rationale The probability of structural remodeling in brain circuits may be modulated by molecules of perineuronal nets (PNNs) that restrict neuronal plasticity to stabilize circuits. Animal research demonstrates that ...