Browsing PSB_Articles by Author "70c44dfb-f229-4d88-9f54-88182632db14"
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A Working Hypothesis for the Role of the Cerebellum in Impulsivity and Compulsivity
MIQUEL, MARTA; Nicola, Saleem; Gil-Miravet, Isis; Guarque-Chabrera, Julian; Sanchez-Hernandez, Aitor Frontiers Media (2019-05)Growing evidence associates cerebellar abnormalities with several neuropsychiatric disorders in which compulsive symptomatology and impulsivity are part of the disease pattern. Symptomatology of autism, addiction, ... -
Cerebellar perineuronal nets in cocaine-induced pavlovian memory: Site matters
Carbó Gas, María; Moreno Rius, Josep; Guarque-Chabrera, Julian; Vázquez Sanromán, Dolores; Gil-Miravet, Isis; Carulli, Daniela; Hoebeek, Freek; De Zeeuw, Chris; Sanchis-Segura, Carla; MIQUEL, MARTA Elsevier (2017-07-14)One of the key mechanisms for the stabilization of synaptic changes near the end of critical periods for experience-dependent plasticity is the formation of specific lattice extracellular matrix structures called perineuronal ... -
Cocaine-Induced Preference Conditioning: a Machine Vision Perspective
Traver Roig, Vicente Javier; Pla, Filiberto; MIQUEL, MARTA; Carbó Gas, María; Gil-Miravet, Isis; Guarque-Chabrera, Julian Springer (2018)Existing work on drug-induced synaptic changes has shown that the expression of perineuronal nets (PNNs) at the cerebellar cortex can be regulated by cocaine-related memory. However, these studies on animals have mostly ... -
Consensus Paper: Cerebellum and Reward
Manto, Mario; Adamaszek, Michael; Apps, Richard; Carlson, Erik; Guarque-Chabrera, Julian; Heleven, Elien; Kakei, Shinji; Khodakhah, Kamran; Kuo, Sheng-Han; Lin, Chi-Ying; Joshua, Mati; MIQUEL, MARTA; Mitoma, Hiroshi; Larry, Noga; Péron, Julie Anne; Pickford, Jasmine; Schutter, Dennis; Singh, Manpreet K.; Tan, Tommy; Tanaka, Hirokazu; tsai, peter; Van Overwalle, Frank; Yamashiro, Kunihiko Springer (2024-05-06)Cerebellum is a key-structure for the modulation of motor, cognitive, social and afective functions, contributing to automatic behaviours through interactions with the cerebral cortex, basal ganglia and spinal cord. The ... -
Neural correlates of cocaine-induced conditioned place preference in the posterior cerebellar cortex
Rodríguez Borillo, Olga; Roselló-Jiménez, Lorena; Guarque-Chabrera, Julian; Palau-Batet, María; Gil-Miravet, Isis; Pastor Medall, Raúl; MIQUEL, MARTA; Font Hurtado, Laura Frontiers Media (2023)Introduction: Addictive drugs are potent neuropharmacological agents capable of inducing long-lasting changes in learning and memory neurocircuitry. With repeated use, contexts and cues associated with consumption can ... -
Putting forward a model for the role of the cerebellum in cocaine-induced pavlovian memory
Melchor Eixea, Ignasi; Guarque-Chabrera, Julian; Sánchez Hernández, Aitor; Ibáñez-Marín, Patricia; Pastor Medall, Raúl; MIQUEL, MARTA Frontiers Media (2023)Substance Use Disorder (SUD) involves emotional, cognitive, and motivational dysfunction. Long-lasting molecular and structural changes in brain regions functionally and anatomically linked to the cerebellum, such as the ... -
Role of Perineuronal nets in the cerebellar cortex in cocaine-induced conditioned preference, extinction, and reinstatement
Guarque-Chabrera, Julian; Sanchez-Hernandez, Aitor; Ibáñez-Marín, Patricia; Melchor Eixea, Ignasi; MIQUEL, MARTA Elsevier Ltd (2022-08-17)Perineuronal nets (PNNs) are cartilage-like structures of extracellular matrix molecules that enwrap in a net-like manner the cell-body and proximal dendrites of special subsets of neurons. PNNs stabilize their incoming ... -
The Cerebellum on Cocaine
MIQUEL, MARTA; Gil-Miravet, Isis; Guarque-Chabrera, Julian Frontiers Media (2020-10-21)The traditional cerebellum’s role has been linked to the high computational demands for sensorimotor control. However, several findings have pointed to its involvement in executive and emotional functions in the last ... -
The role of the cerebellum in drug-cue associative memory: functional interactions with the medial prefrontal cortex
Gil-Miravet, Isis; Guarque-Chabrera, Julian; Carbó Gas, María; Olucha-Bordonau, Francisco E; MIQUEL, MARTA John Wiley (2018-10-02)Drug-induced Pavlovian memories are thought to be crucial for drug addiction because they guide behaviour towards environments with drug availability. Drug-related memory depends on persistent changes in dopamine-glutamate ... -
Time-dependent regulation of perineuronal nets in the cerebellar cortex during abstinence of cocaine-self administration
Sanchez-Hernandez, Aitor; Nicolas, Celine; Gil-Miravet, Isis; Guarque-Chabrera, Julian; Solinas, Marcello; MIQUEL, MARTA Springer (2021-01-03)Rationale The probability of structural remodeling in brain circuits may be modulated by molecules of perineuronal nets (PNNs) that restrict neuronal plasticity to stabilize circuits. Animal research demonstrates that ...