Listar PSB_Articles por autoría "32ce77eb-6858-4be9-a693-08e76b8c568c"
Mostrando ítems 1-6 de 6
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Conditional neural knockout of the adenosine A2A receptor and pharmacological A2A antagonism reduce pilocarpine-induced tremulous jaw movements: Studies with a mouse model of parkinsonian tremor
Salamone, John; Collins-Praino, Lyndsey E.; Pardo Andrés, Marta; Podurgiel, Samantha J.; Baqi, Younis; Müller, Christa E.; Schwarzschild, Michael A.; Correa, Merce Elsevier (2013)Tremulous jaw movements are rapid vertical deflections of the lower jaw that resemble chewing but are not directed at any particular stimulus. In rats, tremulous jaw movements can be induced by a number of conditions that ... -
Induction of oral tremor in mice by the acetylcholinesterase inhibitor galantamine: Reversal with adenosine A2A antagonism
Podurgiel, Samantha J.; Spencer, Tiahna; Kovner, Rotem; Baqi, Younis; Müller, Christa E.; Correa, Merce; Salamone, John Elsevier (2016-01)Tremulous jaw movements (TJMs) have become a commonly used rat model of Parkinsonian tremor. TJMs can be induced by a number of neurochemical conditions that parallel those seen in human Parkinsonism, including DA depletion, ... -
Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors
Nunes, Eric J.; Randall, Patrick A.; Podurgiel, Samantha J.; Correa, Merce; Salamone, John Elsevier (2013)Mesolimbic dopamine (DA) is a critical component of the brain circuitry regulating behavioral activation and effort-related processes. Although nucleus accumbens (NAc) DA depletions or antagonism leave aspects of appetite ... -
The MAO-B inhibitor deprenyl reduces the oral tremor and the dopamine depletion induced by the VMAT-2 inhibitor tetrabenazine
Podurgiel, Samantha J.; Yohn, Samantha E.; Dortche, Kristina; Correa, Merce; Salamone, John Elsevier (2016)Tetrabenazine (TBZ) is prescribed for the treatment of chorea associated with Huntington’s disease. Via inhibition of the vesicular monoamine transporter (VMAT-2), TBZ blocks dopamine (DA) storage and depletes striatal DA; ... -
The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists
Yohn, Samantha E.; Santerre, Jessica L.; Nunes, Eric J.; Kozak, Rouba; Podurgiel, Samantha J.; Correa, Merce; Salamone, John Elsevier (2015)Mesolimbic dopamine (DA), particularly in the nucleus accumbens, is a critical component of the brain circuitry involved in behavioral activation and effort-related processes. Although much is known about the characteristics of ... -
The vesicular monoamine transporter (VMAT-2) inhibitor tetrabenazine induces tremulous jaw movements in rodents: Implications for pharmacological models of parkinsonian tremor
López Cruz, Laura; Podurgiel, Samantha J.; Nunes, Eric J.; Yohn, Samantha E.; Barber, J.; Thompson, A.; Milligan, M.; Lee, Christie A.; Pardo Andrés, Marta; Valverde, Olga; LEDENT, Catherine; Baqi, Younis; Müller, Christa E.; Correa, Merce; Salamone, John Elsevier (2013)Tetrabenazine (TBZ) is a reversible inhibitor of vesicular monoamine storage that is used to treat Huntington’s disease. TBZ preferentially depletes striatal dopamine (DA), and patients being treated with TBZ often experience ...