Listar LSI_Articles por autoría "20cbfd6f-e235-46af-a4ed-69f9a8df41c7"
Mostrando ítems 21-32 de 32
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Inverse association between habitual polyphenol intake and incidence of cardiovascular events in the PREDIMED study
Tresserra-Rimbau, Anna; Rimm, Eric B.; Medina Remón, A.; Martínez González, Miguel Ángel; De la Torre, R.; Corella, Dolores; Salas-Salvadó, Jordi; Gómez Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol Ramis, Miquel; Ros, Emilio; Serra-Majem, Lluis; Pintó, Xavier; Sáez Tormo, Guillermo; Basora, Josep; Sorlí, José V; Martínez, J. Alfredo; Vinyoles, E.; Ruiz-Gutiérrez, Valentina; Estruch, Ramon; Lamuela Raventós, Rosa María; Coltell, Oscar Elsevier (2016-06)Background and aims Epidemiologic and biological evidence supports an inverse association between polyphenol consumption and the risk of cardiovascular disease (CVD). However, no previous studies have prospectively ... -
Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence
Corella, Dolores; Carrasco, Paula; Sorlí, José V; Estruch, Ramon; Rico Sanz, Jesús; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Covas Planells, María Isabel; Coltell, Oscar; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Warnberg, Julia; Fiol Ramis, Miquel; Pintó, Xavier; CAROLINA, ORTEGA-AZORÍN; Muñoz, Miguel Ángel; Martínez, J. Alfredo; Gómez Gracia, Enrique; González, José I.; Ros, Emilio; Ordovás Muñoz, José M. American Diabetes Association (2013)OBJECTIVE Transcription factor 7-like 2 (TCF7L2) polymorphisms are strongly associated with type 2 diabetes, but controversially with plasma lipids and cardiovascular disease. Interactions of the Mediterranean diet (MedDiet) ... -
MicroRNA-410 regulated lipoprotein lipase variant rs13702 is associated with stroke incidence and modulated by diet in the randomized controlled PREDIMED trial
Corella, Dolores; Sorlí, José V; Estruch, Ramon; Coltell, Oscar; CAROLINA, ORTEGA-AZORÍN; Portolés, Olga; Martínez González, Miguel Ángel; Bulló, Mònica; Fitó, Montserrat; Arós, Fernando; Lapetra, José; Asensio, Eva Maria; Sáez Tormo, Guillermo; Serra-Majem, Lluis; Muñoz Bravo, Carlos; Ruiz-Gutiérrez, Valentina; Fiol Ramis, Miquel; Vinyoles, Ernest; Pintó, Xavier; Richardson, Kris; Ros, Emilio; Ordovás Muñoz, José M. American Society for Nutrition (2014-08)Background: MicroRNAs have emerged as important epigenetic regulators in cardiovascular diseases (CVDs). Using an observational meta-analysis design, we previously characterized a gain-of-function microRNA-410 target site ... -
MicroRNAs and Drinking: Association between the Pre-miR-27a rs895819 Polymorphism and Alcohol Consumption in a Mediterranean Population
Barragán-Arnal, Rocío; Coltell, Oscar; Asensio, Eva Maria; Francés, Francesc; Sorlí, José V; Estruch, Ramon; Salas Huetos, Albert; Ordovás Muñoz, José M.; Corella, Dolores MDPI (2016)Recently, microRNAs (miRNA) have been proposed as regulators in the different processes involved in alcohol intake, and differences have been found in the miRNA expression profile in alcoholics. However, no study has ... -
Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial
Corella, Dolores; Sorlí, José V; González, José I.; CAROLINA, ORTEGA-AZORÍN; Fitó, Montserrat; Bulló, Mònica; Martínez González, Miguel Ángel; Ros, Emilio; Arós, Fernando; Lapetra, José; Gómez Gracia, Enrique; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Fiol Ramis, Miquel; Coltell, Oscar; Vinyoles, Ernest; Pintó, Xavier; Martí, Amelia; Sáiz, Carmen; Ordovás Muñoz, José M.; Estruch, Ramon BioMed Central (2014-01)Background: The Fas apoptotic pathway has been implicated in type 2 diabetes and cardiovascular disease. Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related ... -
Nutritional adequacy according to carbohydrates and fat quality
Sánchez-Tainta, Ana; Zazpe, Itziar; Bes-Rastrollo, Maira; Salas-Salvadó, Jordi; Bulló, Mònica; Sorlí, José V; Corella, Dolores; Covas Planells, María Isabel; Arós, Fernando; Gutiérrez-Bedmar, Mario; Fiol Ramis, Miquel; De la Corte, F. García; Serra-Majem, Lluis; Pintó, Xavier; Schoreder, Helmut; Ros, Emilio; López-Sabater, Maria Carmen; Estruch, Ramon; Martínez González, Miguel Ángel; Coltell, Oscar Springer Verlag (2016)Purpose To investigate the association between carbohydrate quality, fat quality or adherence to the Mediterranean diet and intake adequacy of 19 micronutrients in the PREDIMED (PREvención con DIeta MEDiterránea) trial, ... -
Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores
Corella, Dolores; Coltell, Oscar; Sorlí, José V; Estruch, Ramon; Quiles Guiñau, Laura; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Castañer, Olga; Arós, Fernando; Ortega-Calvo, Manuel; Serra-Majem, Lluis; Gómez Gracia, Enrique; Portolés, Olga; Fiol Ramis, Miquel; Díez Espino, Javier; Basora, Josep; Fitó, Montserrat; Ros, Emilio; Ordovás Muñoz, José M. MDPI (2016)Nutrigenetic studies analyzing gene–diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by ... -
PPAR-α L162V and PGC-1 G482S gene polymorphisms, but not PPAR-γ P12A, are associated with alcohol consumption in a Spanish Mediterranean population
Francés, F.; Verdú, Fernando; Portolés, Olga; Castello, A.; Sorlí, José V; Guillen, M.; Corella, Dolores Elsevier (2008)Background: Peroxisome Proliferator-Activated Receptors (PPARs) and its co-activators are regulatory elements of the cellular lipid homeostasis and have been associated with feeding behavior modulation. Animal models suggest ... -
Single and Combined Associations of Plasma and Urine Essential Trace Elements (Zn, Cu, Se, and Mn) with Cardiovascular Risk Factors in a Mediterranean Population
Barragán-Arnal, Rocío; Sánchez González, Cristina; Aranda, Pilar; Sorlí, José V; Asensio, Eva Maria; Portolés, Olga; Ortega-Azorín, Carolina; Villamil, Laura V.; Coltell, Oscar; Llopis, Juan; Rivas García, Lorenzo; Corella, Dolores (2022-10)Trace elements are micronutrients that are required in very small quantities through diet but are crucial for the prevention of acute and chronic diseases. Despite the fact that initial studies demonstrated inverse ... -
Single tube optimisation of APOE genotyping based on melting curve analysis
Francés, F.; Portolés, Olga; Sorlí, José V; Guillen, M.; González, José I.; Corella, Dolores Elsevier (2008)Objectives: To develop and validate a single-tube protocol for APOE genotyping using fluorescent probes. Design and methods: We have designed and validated a hybrid, single-tube, SimpleProbe/FRET probe protocol that takes ... -
Statistical and biological gene-lifestyle interactions of MC4R and FTO with Diet and physical activity on obesity: new effects on alcohol consumption
Corella, Dolores; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Covas Planells, María Isabel; Carrasco, Paula; Salas-Salvadó, Jordi; Martínez González, Miguel Ángel; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Lamuela Raventós, Rosa María; Gómez García, Enrique; Fiol Ramis, Miquel; Pintó, Xavier; Ros, Emilio; Martí, Amelia; Coltell, Oscar; Ordovás Muñoz, José M.; Estruch, Ramon Public Library of Science (2012)Background: Fat mass and obesity (FTO) and melanocortin-4 receptor (MC4R) and are relevant genes associated with obesity. This could be through food intake, but results are contradictory. Modulation by diet or other ... -
Utilizing nutritional genomics to tailor diets for the prevention of cardiovascular disease: a guide for upcoming studies and implementations
Corella, Dolores; Coltell, Oscar; Mattingley, George; Sorlí, José V; Ordovás Muñoz, José M. Taylor & Francis (2017-04-03)Introduction: Personalized diets based on an individual’s genome to optimize the success of dietary intervention and reduce genetic cardiovascular disease (CVD) risk, is one of the challenges most frequently discussed in ...