• openAccess   Influence of calcium ion-modified implant surfaces in protein adsorption and implant integration 

      Anitua, Eduardo; Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Azkagorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio; Tejero, Ricardo Springer (2021-04-21)
      Calcium (Ca) is a well-known element in bone metabolism and blood coagulation. Here, we investigate the link between the protein adsorption pattern and the in vivo responses of surfaces modified with calcium ions (Ca-ion) ...
    • openAccess   Influence of zinc molybdenum phosphate pigment on coatings performance studied by electrochemical methods 

      Molina Castellanos, Javier; Puig Brugal, Montserrat; Gimeno Pérez, María José; Izquierdo Escrig, Raul; Gracenea Zapirain, José Javier; Suay, Julio Elsevier (2016-08)
      The effect of the addition of the zinc molybdenum phosphate pigment, on the corrosion resistance properties of powder coating on steel, has been investigated by means of different electrochemical methods: electrochemical ...
    • openAccess   Insight into the antibacterial mechanism of Cu-enriched sol–gel coatings employing proteomics 

      Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Cerqueira, Andreia; Scalschi, Loredana; Vicedo, Begonya; Villagrasa, Alejandro; Izquierdo, Raúl; Elortza, Felix; Gurruchaga, Mariló; Goñi, Isabel; Suay, Julio Royal Society of Chemistry (2023)
      Advanced antibacterial biomaterials can help reduce the severe consequences of infections. Using copper compounds is an excellent option to achieve this goal; they offer a combination of regenerative and antimicrobial ...
    • closedAccess   Optimization of deposition voltage of cataphoretic automotive primers assessed by EIS and AC/DC/AC 

      García, S. J.; Suay, Julio Elsevier (2009)
      The dependence of the anticorrosive properties of a cataphoretic paint with the applied deposition voltage was studied by the so-called EIS tests; an accelerated cyclic test used in the automotive industry; and a rapid ...
    • openAccess   Osseointegration mechanisms: a proteomic approach 

      Gomes, Nuno; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Sánchez-Pérez, Ana María; Azkargorta, Mikel; Elortza, Felix; Martín de Llano, J.J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer-Verlag (2018-03)
      The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ...
    • openAccess   Osteointegración de implantes de titanio con superficies activas. Un estudio proteómico 

      Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Ediciones Peldaño (2017-12)
      Titanium is a biomaterial largely used on dental implant manufacturing. However, as a consequence of its intrinsically low bioactivity, the development of distinct superficial treatments in order to enhance its ...
    • openAccess   Protein adsorption/desorption dynamics on Ca‑enriched titanium surfaces: biological implications 

      Romero-Gavilán, Francisco J; Cerqueira, Andreia; Anitua, Eduardo; Tejero, Ricardo; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Izquierdo Escrig, Raul; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer (2021-08-27)
      Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant ...
    • openAccess   Proteome analysis of human serum proteins adsorbed onto different titanium surfaces used in dental implants 

      Romero-Gavilán, Francisco J; Gomes, N. C.; Ródenas, Joaquin; Sánchez, Ana; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; García-Arnáez, Iñaki; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Taylor & Francis (2017)
      Titanium dental implants are commonly used due to their biocompatibility and biochemical properties; blasted acid-etched Ti is used more frequently than smooth Ti surfaces. In this study, physico-chemical characterisation ...
    • openAccess   Proteomic analysis of calcium-enriched sol–gel biomaterials 

      Romero-Gavilán, Francisco J; Gomes, Nuno; Cerqueira, Andreia; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Springer (2019-04)
      Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ...
    • openAccess   Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating 

      Cerqueira, Andreia; Romero-Gavilán, Francisco J; Helmholz, Heike; Azkargorta, Mikel; Elortza, Félix; Gurruchaga, Mariló; Goñi, Isabel; Willumeit-Römer, Regine; Suay, Julio American Chemical Society (2023)
      New methodologies capable of extensively analyzing the cell-material interactions are necessary to improve current in vitro characterization methods, and proteomics is a viable alternative. Also, many studies are focused ...
    • openAccess   Proteomic analysis of silica hybrid sol-gel coatings: a potential tool for predicting the biocompatibility of implants in vivo 

      Romero-Gavilán, Francisco J; Sánchez-Pérez, Ana María; Gomes, Nuno; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; Gurruchaga, Marilo; Goñi, Isabel; Suay, Julio Taylor & Francis (2017)
      The interactions of implanted biomaterials with the host organism determine the success or failure of an implantation. Normally, their biocompatibility is assessed using in vitro tests. Unfortunately, in vitro and in vivo ...
    • openAccess   Proteomic evaluation of human osteoblast responses to titanium implants over time 

      Romero-Gavilán, Francisco J; Cerqueira, Andreia; García-Arnáez, Iñaki; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Wiley (2022-08-30)
      Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human ...
    • openAccess   Proteomics as a tool to study the osteoimmunomodulatory role of metallic ions in a sol–gel coating 

      García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Cerqueira, Andreia; Azkargorta, Mikel; Elortza, Félix; Suay, Julio; Goñi, Isabel; Gurruchaga, Mariló Royal Society of Chemistry (2023)
      The success of bone implants depends on the osteoimmunomodulatory (OIM) activity of the biomaterials in the interactions with the periimplantary tissues. Many in vitro tests have been conducted to evaluate the osteoimmunology ...
    • openAccess   Silica-gelatin hybrid sol-gel coatings: A proteomic study with biocompatibility implications 

      Gomes, Nuno; Romero-Gavilán, Francisco J; Lara, Irene; Elortza, Felix; Azkargorta, Mikel; Lloro, Ibon; Ibáñez, Maria; Martín de Llano, J. J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio; Sánchez-Pérez, Ana María Wiley (2018-05)
      Osseointegration, including the foreign body reaction to biomaterials, is an immune‐modulated, multifactorial, and complex healing process in which various cells and mediators are involved. The buildup of the osseointegration ...
    • openAccess   Sol-gel coatings for metallic prosthesis from methyl-modified alkoxysilanes: balance between protection and bioactivation 

      Romero-Gavilán, Francisco J; Carlos-Almeida, J.; Cerqueira, Andreia; GURRUCHAGA, MARILO; Goñi, Isabel; Miranda-Salvado, I. M.; Vaz Fernandes, M. H.; Suay, Julio Elsevier (2020)
      The reported osteogenic properties of the hybrid silica sol-gel materials make these compositions perfect candidates for bone tissue engineering applications. The aim of this study was the synthesis and characterisation ...
    • closedAccess   Study of the degradation of hybrid sol–gel coatings in aqueous medium 

      Suay, Julio; Cabedo, Luis; Hernández Escolano, Miriam; Juan Díaz, M.; Martínez Ibáñez, M.; Izquierdo Escrig, Raul; GURRUCHAGA, MARILO; Goñi, Isabel Elsevier (2014-11)
      The design and development of suitable multilayered functional coatings for delaying corrosion advance in metals and become controlled-release vehicles requires that the properties of the coatings are known. Coatings ...
    • openAccess   Study of the thermal degradation of bioactive sol–gel coatings for the optimization of its curing process 

      Suay, Julio; Hernández Escolano, Miriam; Ramis Juan, Xavier; Jiménez Morales, Antonia; Juan Díaz, M. Akadémiai Kiadó (2012-02)
      A set of materials has been prepared by sol–gel process containing different quantities of hydroxyapatite (0, 2.5 and 5% HAp w/w) using as silica precursors glycidyloxypropyltrimethoxysilane (GPTMS) and triethoxyvinyl ...
    • openAccess   Synthesis and characterization of silica-chitosan hybrid materials as antibacterial coatings for titanium implants 

      Palla-Rubio, B.; Gomes, Nuno; Fernández Gutiérrez, Mar; Rojo, Luis; Suay, Julio; Gurruchaga, Mariló; Goñi, Isabel Elsevier (2019-01)
      To avoid dental implant-related infections and to promote the osseointegration of titanium implants, the application of silicon and chitosan containing coatings is proposed. Silicon is a well-known osteogenic element and ...
    • closedAccess   Synthesis of hybrid sol-gel materials and their biological evaluation with human mesenchymal stem cells 

      Hernández Escolano, Miriam; Juan Díaz, M.; Martínez Ibáñez, M.; Suay, Julio; Goñi, Isabel; GURRUCHAGA, MARILO Springer (2013-03)
      Surface engineering of biomaterials could promote the osseointegration of implants. In this work, two types of hybrid sol–gel materials were developed to stimulate cell attachment, proliferation and differentiation of ...
    • closedAccess   The combined role of inhibitive pigment and organo-modified silica particles on powder coatings: Mechanical and electrochemical investigation 

      Puig Brugal, Montserrat; Cabedo, Luis; Gracenea Zapirain, José Javier; Suay, Julio Elsevier (2015)
      The addition of organo-modified silica particles (OSP) to powder coating containing zinc molybdenum phosphate pigment (ZMP) has been investigated. The OSP were directly incorporated at different concentrations (1, 2.5, 3.5 ...