• openAccess   Insight into the antibacterial mechanism of Cu-enriched sol–gel coatings employing proteomics 

      Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Cerqueira, Andreia; Scalschi, Loredana; Vicedo, Begonya; Villagrasa, Alejandro; Izquierdo, Raúl; Elortza, Felix; Gurruchaga, Mariló; Goñi, Isabel; Suay, Julio Royal Society of Chemistry (2023)
      Advanced antibacterial biomaterials can help reduce the severe consequences of infections. Using copper compounds is an excellent option to achieve this goal; they offer a combination of regenerative and antimicrobial ...
    • openAccess   Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating 

      Cerqueira, Andreia; Romero-Gavilán, Francisco J; Helmholz, Heike; Azkargorta, Mikel; Elortza, Félix; Gurruchaga, Mariló; Goñi, Isabel; Willumeit-Römer, Regine; Suay, Julio American Chemical Society (2023)
      New methodologies capable of extensively analyzing the cell-material interactions are necessary to improve current in vitro characterization methods, and proteomics is a viable alternative. Also, many studies are focused ...
    • openAccess   Proteomics as a tool to study the osteoimmunomodulatory role of metallic ions in a sol–gel coating 

      García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Cerqueira, Andreia; Azkargorta, Mikel; Elortza, Félix; Suay, Julio; Goñi, Isabel; Gurruchaga, Mariló Royal Society of Chemistry (2023)
      The success of bone implants depends on the osteoimmunomodulatory (OIM) activity of the biomaterials in the interactions with the periimplantary tissues. Many in vitro tests have been conducted to evaluate the osteoimmunology ...
    • openAccess   Using osteogenic medium in the in vitro evaluation of bone biomaterials: Artefacts due to a synergistic effect 

      Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Cerqueira, Andreia; Arias-Mainer, Carlos; Azkargorta, Mikel; Elortza, Felix; Izquierdo, Raúl; Gurruchaga, Mariló; Goñi, Isabel Elsevier (2023)
      In vitro tests using bone cells to evaluate the osteogenic potential of biomaterials usually employ the osteogenic medium (OM). The lack of correlation frequently reported between in vitro and in vivo studies in bone ...