Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: A multicenter, controlled, randomized study
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Otros documentos de la autoría: López-del-Hoyo, Yolanda; Oliván, Barbara; Luciano, Juan Vicente; Mayoral-Cleries, Fermin; Roca, Miquel; Gili, Margalida; Andrés, Eva; Serrano Blanco, Antoni; Collazo, Francisco; Araya, Ricardo; Baños, Rosa Maria; Botella, Cristina; Magallón, Rosa; Garcia-Campayo, Javier
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Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: A multicenter, controlled, randomized studyAutoría
Fecha de publicación
2013-01-11Editor
BioMed CentralISSN
1471-244X; 1471-244XCita bibliográfica
LÓPEZ-DEL-HOYO, Yolanda, et al. Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: a multicenter, controlled, randomized study. BMC psychiatry, 2013, vol. 13, no 1, p. 21Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://www.biomedcentral.com/1471-244X/13/21Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
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Background: Major depression will become the second most important cause of disability in 2020. Computerized
cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies ... [+]
Background: Major depression will become the second most important cause of disability in 2020. Computerized
cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies on costeffectiveness of low intensity vs self-guided psychotherapy has been carried out. The aim of this study is to assess
the efficacy of low intensity vs self-guided psychotherapy for major depression in the Spanish health system.
Methods: The study is made up of 3 phases: 1.- Development of a computerized cognitive-behaviour therapy for
depression tailored to Spanish health system. 2.- Multicenter controlled, randomized study: A sample (N=450
patients) with mild/moderate depression recruited in primary care. They should have internet availability at home,
not receive any previous psychological treatment, and not suffer from any other severe somatic or psychological
disorder. They will be allocated to one of 3 treatments: a) Low intensity Internet-delivered psychotherapy +
improved treatment as usual (ITAU) by GP, b) Self-guided Internet-delivered psychotherapy + ITAU or c) ITAU.
Patients will be diagnosed with MINI psychiatric interview. Main outcome variable will be Beck Depression
Inventory. It will be also administered EuroQol 5D (quality of life) and Client Service Receipt Inventory (consume of
health and social services). Patients will be assessed at baseline, 3 and 12 months. An intention to treat and a per
protocol analysis will be performed.
Discussion: The comparisons between low intensity and self-guided are infrequent, and also a comparative
economic evaluation between them and compared with usual treatment in primary. The strength of the study is
that it is a multicenter, randomized, controlled trial of low intensity and self-guided Internet-delivered
psychotherapy for depression in primary care, being the treatment completely integrated in primary care setting.
Trial registration: Clinical Trials NCT01611818 [-]
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BMC Psychiatry (2013), Vol. 13, no. 1Derechos de acceso
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