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The MAO-B inhibitor deprenyl reduces the oral tremor and the dopamine depletion induced by the VMAT-2 inhibitor tetrabenazine
(Elsevier, 2016)
Tetrabenazine (TBZ) is prescribed for the treatment of chorea associated with Huntington’s disease. Via inhibition of the vesicular monoamine transporter (VMAT-2), TBZ blocks dopamine (DA) storage and depletes striatal DA; ...
An Internet based intervention for improving resilience and coping strategies in university students: Study protocol for a randomized controlled trial
(Elsevier, 2018-03)
Background
The literature shows a high prevalence of depression and anxiety in young people. The university represents a change in the lives of students, and is considered a stress factor. Therefore, it is particularly ...
Efficacy and cost-effectiveness of guided and unguided internet- and mobilebased indicated transdiagnostic prevention of depression and anxiety (ICare Prevent): A three-armed randomized controlled trial in four European countries
(Elsevier, 2018-04)
Background
Depression and anxiety are highly prevalent and often co-occur. Several studies indicate the potential of disorder-specific psychological interventions for the prevention of each of these disorders. To treat ...
Assessing the costs and cost-effectiveness of ICare internet-based interventions (protocol)
(Elsevier, 2018-02)
Background
Mental health problems are common and place a burden on the individual as well as on societal resources. Despite the existence of evidence-based treatments, access to treatment is often prevented or delayed ...
Meditation experts try Virtual Reality Mindfulness: A pilot study evaluation of the feasibility and acceptability of Virtual Reality to facilitate mindfulness practice in people attending a Mindfulness conference
(Public Library of Science, 2017)
Regular mindfulness practice benefits people both mentally and physically, but many populations who could benefit do not practice mindfulness. Virtual Reality (VR) is a new technology that helps capture participants’ ...
Is self-guided internet-based cognitive behavioural therapy (iCBT) harmful? An individual participant data meta-analysis
(Cambridge University Press, 2018)
Background. Little is known about potential harmful effects as a consequence of self-guided
internet-based cognitive behaviour therapy (iCBT), such as symptom deterioration rates.
Thus, safety concerns remain and hamper ...
Dopamine depletion shifts behavior from activity based reinforcers tomore sedentary ones and adenosine receptor antagonism reversesthat shift: Relation to ventral striatum DARPP32 phosphorylationpatterns
(Elsevier, 2018)
The mesolimbic dopamine (DA) system plays a critical role in behavioral activation and effort-baseddecision-making. DA depletion produces anergia (shifts to low effort options) in animals tested oneffort-based decision-making ...
Effects of the Best Possible Self intervention: A systematic review and meta-analysis
(Public Library of Science, 2019)
The Best Possible Self (BPS) exercise promotes a positive view of oneself in the best possible future, after working hard towards it. Since the first work that attempted to examine the
benefits of this intervention in ...
Validation of the AIDS Prevention Questionnaire: A Brief Self-Report Instrument to Assess Risk of HIV Infection and Guide Behavioral Change
(Springer, 2018)
This paper describes the process of building and validating the AIDS Prevention Questionnaire (CPS), a brief HIV risk assessment measure. An initial 64-items bank was filled out by 466 young people (192 men and 274 women), ...
The role of the cerebellum in drug-cue associative memory: functional interactions with the medial prefrontal cortex
(John WileyFederation of European Neuroscience Societie, 2018-10-02)
Drug-induced Pavlovian memories are thought to be crucial for drug addiction because they guide behaviour towards environments
with drug availability. Drug-related memory depends on persistent changes in dopamine-glutamate ...