Hippocampal shape analysis in Alzheimer’s disease using Functional Data Analysis
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Título
Hippocampal shape analysis in Alzheimer’s disease using Functional Data AnalysisFecha de publicación
2013Editor
Wiley-BlackwellISSN
0277-6715; 1097-0258Cita bibliográfica
Epifanio, I. and Ventura-Campos, N. (2013), Hippocampal shape analysis in Alzheimer's disease using functional data analysis. Statist. Med.. doi: 10.1002/sim.5968Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://onlinelibrary.wiley.com/doi/10.1002/sim.5968/fullVersión
info:eu-repo/semantics/submittedVersionPalabras clave / Materias
Resumen
The hippocampus is one of the first affected regions in Alzheimer's disease. The left hippocampi of control subjects, patients with mild cognitive impairment and patients with Alzheimer's disease are represented by ... [+]
The hippocampus is one of the first affected regions in Alzheimer's disease. The left hippocampi of control subjects, patients with mild cognitive impairment and patients with Alzheimer's disease are represented by spherical harmonics. Functional data analysis is used in the hippocampal shape analysis. Functional principal component analysis and functional independent component analysis are defined for multivariate functions with two arguments. A functional linear discriminant function is also defined. Comparisons with other approaches are carried out. Our functional approach gives promising results, especially in shape classification. Copyright © 2013 John Wiley & Sons, Ltd. [-]
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Statistics in Medicine, 2013. doi: 10.1002/sim.5968Derechos de acceso
Copyright © 2013 John Wiley & Sons, Ltd.
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info:eu-repo/semantics/openAccess
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/openAccess
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