Visualitza Departament: Química Inorgànica i Orgànica per paraule clau "tumor microenvironment"

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    • openAccess   Aryl azoles based scaffolds for disrupting tumor microenvironment 

      Pla López, Alberto; Martinez-Colomina, Paula; Cañada-García, Laura; Fuertes-Monge, Laura; Orellana-Palacios, Jose C.; Valderrama-Martínez, Alejandro; Pérez Sosa, Marikena; Carda, Miguel; Falomir, Eva Elsevier (2023-11-15)
      Thirty-nine aryl azoles, thirteen triazoles and twenty-seven tetrazoles, have been synthetized and biologically evaluated to determine their activity as tumor microenvironment disruptors. Antiproliferative studies have ...

    • openAccess   Unveiling the Potential of BenzylethyleneAryl–Urea Scaffolds for the Design of New Onco Immunomodulating Agents 

      Gil-Edo, Raquel; Royo, Santiago; Carda, Miguel; Falomir, Eva MDPI (2023)
      This work focuses on the development of thirteen benzylethylenearyl ureas and one carbamate. After the synthesis and purification of the compounds, we studied their antiproliferative action on cell lines, such as HEK-293, ...