• closedAccess   A Chalcone-Based Highly Selective and Sensitive Chromofluorogenic Probe for Trivalent Metal Cations 

      Santos-Figueroa, Luis E.; Llopis-Lorente, Antoni; Royo Calvo, Santiago; Sancenón, Félix; Martinez-Manez, Ramon; Costero, Ana M.; Gil, Salvador; Parra, Margarita Wiley (2017)
      A new chalcone-based probe for the chromofluorogenic sensing of trivalent (Al3+, Fe3+, Cr3+, Ga3+, In3+ and As3+) over mono- and divalent cations and anions is reported. In the presence of trivalent metal cations, the probe ...
    • openAccess   Continuous Flow Processes as an Enabling Tool for the Synthesis of Constrained Pseudopeptidic Macrocycles 

      Esteve Franch, Ferran; Porcar Garcia, Raul; Luis, Santiago V.; Altava, Belen; Garcia-Verdugo, Eduardo American Chemical Society (2022-02-15)
      Herein we report our efforts to develop a continuous flow methodology for the efficient preparation of pseudopeptidic macrocyclic compounds containing the hexahydropyrrolo-[3,4-f]-isoindolocyclophane scaffold and involving ...
    • openAccess   Rim, Side Arms, and Cavity: Three Sites for the Recognition of Anions by Tetraazolium Resorcinarene Cavitands 

      Ruiz-Botella, Sheila; Vidossich, Pietro; Ujaque, Gregori; Peris, Eduardo Wiley (2016-09)
      Two tetrabenzoimidazolium-resorcinarene cavitands were prepared and used for the recognition of chloride, bromide, iodide, cyanide, nitrate, perchlorate, hexanoate, benzenesulfonate, and p-toluenesulfonate. Binding affinities ...
    • openAccess   Self-assembled multivalent (SAMul) ligand systems with enhanced stability in the presence of human serum 

      Tena Solsona, Marta; Marson, Domenico; Rodrigo, Ana C.; Bromfield, Stephen M.; Escuder, Beatriu; Miravet, Juan; Apostolova, Nadezda; Laurini, Erik; Pricl, Sabrina Royal Society of Chemistry (2019)
      Self-assembled cationic micelles are an attractive platform for binding biologically-relevant polyanions such as heparin. This has potential applications in coagulation control, where a synthetic heparin rescue agent could ...
    • closedAccess   Tight and Selective Caging of Chloride Ions by a Pseudopeptidic Host 

      Martí Vidal, Inés; Bolte, Michael; Burguete, M. Isabel; Vicent Barrera, Cristian; Alfonso Rodríguez, Ignacio; Luis, Santiago V. WILEY-VCH Verlag GmbH & Co. KGaA (2014-06)
      The selective molecular recognition of chloride versus similar anions is a continuous challenge in supramolecular chemistry. We have designed and prepared a simple pseudopeptidic cage (1 a) that defines a cavity suitable ...