ListarDepartament: Química Inorgànica i Orgànica por tema "THP-1"
Mostrando ítems 1-3 de 3
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Styryl carbamate backbones for the discovery of TME-disrupting agents
Elsevier (2024)Twenty-one styryl carbamates have been designed, synthetized and characterized by their physical properties. Afterwards, their potential activity as tumor microenvironment disruptors has been evaluated. First, antiproliferative ... -
Tetrazole derivatives as potent immunomodulatory agents in tumor microenvironment
Elsevier (2023-11-01)Twenty-seven compounds bearing a tetrazole ring as a central unit have been designed, synthetized and biologically evaluated. Studies have been performed in order to compare the effect of tetrazole derivatives bearing amine ... -
Unveiling the Potential of BenzylethyleneAryl–Urea Scaffolds for the Design of New Onco Immunomodulating Agents
MDPI (2023)This work focuses on the development of thirteen benzylethylenearyl ureas and one carbamate. After the synthesis and purification of the compounds, we studied their antiproliferative action on cell lines, such as HEK-293, ...