Browsing Departament: Química Inorgànica i Orgànica by Keyword "Antineoplastic agents"
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Synthesis and biological properties of the cytotoxic 14-membered macrolides aspergillide A and B
Wiley (2010-11-09)Total, stereoselective syntheses of the naturally occurring, cytotoxic macrolides aspergillide A and B are described. Olefin metatheses and asymmetric allylations were key steps in the synthetic sequences. Cytotoxicity ...