• openAccess   Bioactive potential of silica coatings and its effect on the adhesion of proteins to titanium implants 

      Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Elortza, Felix; Azkargorta, Mikel; Martín de Llano, J.J.; Carda, C.; Gurruchaga, Marilo; Suay, Julio; Goñi, Isabel Elsevier (2018-02-01)
      There is an ever-increasing need to develop dental implants with ideal characteristics to achieve specific and desired biological response in the scope of improve the healing process post-implantation. Following that ...
    • openAccess   Complex effects of Mg-biomaterials on the osteoblast cell machinery: A proteomic study 

      Cerqueira, Andreia; García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Azkargorta, Mikel; Elortza, Felix; Martín de Llanos, José Javier; Carda, Carmen; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Elsevier (2022)
      The cell–biomaterial interface is highly complex; thousands of molecules and many processes participate in its formation. Growing demand for improved biomaterials has highlighted the need to understand the structure and ...
    • openAccess   Development and characterisation of strontium-doped sol-gel coatings to optimise the initial bone regeneration processes 

      García-Arnáez, Iñaki; Cerqueira, Andreia; Romero-Gavilán, Francisco J; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; Suay, Julio; Goñi, Isabel; GURRUCHAGA, MARILO Elsevier (2022)
      Strontium plays an important role in bone regeneration; it promotes the differentiation and maturation of osteoblasts and inhibits the activity of osteoclasts. Our principal objective in this study was to formulate new ...
    • openAccess   Enhancement of plasma protein adsorption and osteogenesis of hMSCs by functionalized siloxane coatings for titanium implants 

      Ibáñez, Maria; Sanjeeva Murthy, N.; Mao, Yong; Suay, Julio; GURRUCHAGA, MARILO; Goñi, Isabel; Kohn, Joachim Wiley (2018-03)
      A series of sol–gel derived silicon based coatings were developed to improve the osseointegration of commer- cial titanium dental implants. The osseointegration starts with a positive interaction between the implant ...
    • openAccess   Osseointegration mechanisms: a proteomic approach 

      Gomes, Nuno; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Sánchez-Pérez, Ana María; Azkargorta, Mikel; Elortza, Felix; Martín de Llano, J.J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer-Verlag (2018-03)
      The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ...
    • openAccess   The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions 

      Romero-Gavilán, Francisco J; Gomes, Nuno; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2019-02-01)
      It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...
    • openAccess   Using osteogenic medium in the in vitro evaluation of bone biomaterials: Artefacts due to a synergistic effect 

      Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Cerqueira, Andreia; Arias-Mainer, Carlos; Azkargorta, Mikel; Elortza, Felix; Izquierdo, Raúl; Gurruchaga, Mariló; Goñi, Isabel Elsevier (2023)
      In vitro tests using bone cells to evaluate the osteogenic potential of biomaterials usually employ the osteogenic medium (OM). The lack of correlation frequently reported between in vitro and in vivo studies in bone ...