Visualitza Departament: Química Física i Analítica by font "ChemBioChem, 2019, vol. 20, no 22"

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Heavy Enzymes and the Rational Redesign of Protein Catalysts

Scott, Alan; Luk, Louis Y. P.; Tuñón, Iñaki; Moliner, Vicent; Allemann, Rudolf K. Wiley (2019-11-18)

An unsolved mystery in biology concerns the link between enzyme catalysis and protein motions. Comparison between isotopically labelled “heavy” dihydrofolate reductases and their natural‐abundance counterparts has suggested ...