ListarFCA_Articles por tema "biophysics"
Mostrando ítems 1-2 de 2
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Big dynorphin is a neuroprotector scaffold against amyloid β-peptide aggregation and cell toxicity
Elsevier (2022)Amyloid β-peptide (Aβ) misfolding into β-sheet structures triggers neurotoxicity inducing Alzheimer’s disease (AD). Molecules able to reduce or to impair Aβ aggregation are highly relevant as possible AD treatments since ... -
Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold
Elsevier (2023-12-29)TRP channels are important pharmacological targets in physiopathology. TRPV2 plays distinct roles in cardiac and neuromuscular function, immunity, and metabolism, and is associated with pathologies like muscular dystrophy ...