ListarFCA_Articles por tema "Ion channel"
Mostrando ítems 1-8 de 8
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Analysis of SARS-CoV E protein ion channel activity by tuning the protein and lipid charge
Elsevier (2013-05-18)A partial characterization of the ion channels formed by the SARS coronavirus (CoV) envelope (E) protein was previously reported (C. Verdiá-Báguena et al., 2012 [12]). Here, we provide new significant insights on the ... -
Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids
Elsevier (2012-10)Coronavirus (CoV) envelope (E) protein ion channel activity was determined in channels formed in planar lipid bilayers by peptides representing either the transmembrane domain of severe acute respiratory syndrome CoV ... -
Experimental demonstration of charge inversion in a protein channel in the presence of monovalent cations
Elsevier (2014-11)Charge inversion takes place when interfacial charges attract counterions in excess of their own nominal charge. To date, this phenomenon has been reported in a variety of membrane channel systems in the presence of ... -
Insights on the permeability of wide protein channels: measurement and interpretation of ion selectivity
Royal Society of Chemistry (2012-10-11)Ion channels are hollow proteins that have evolved to exhibit discrimination between charged solutes. This property, known as ion selectivity is critical for several biological functions. By using the bacterial porin OmpF ... -
Linearity, saturation and blocking in a large multiionic channel: divalent cation modulation of the OmpF porin conductance
Elsevier (2011-01)Measurement of unitary conductance is a fundamental step in the characterization of a protein ion channelpermeabilizing a membrane. We study here the effect of salts of divalent cations on the OmpF channelconductance ... -
MERS coronavirus envelope protein has a single transmembrane domain that forms pentameric ion channels
Elsevier (2015-04)The Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly identified pathogen able of human transmission that causes a mortality of almost 40%. As in the case of SARS-CoV, MERS virus lacking E protein represents ... -
Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome
Elsevier (2015-11)Severe acute respiratory syndrome coronavirus (SARS-CoV) envelope (E) protein is a viroporin involved in virulence. E protein ion channel (IC) activity is specifically correlated with enhanced pulmonary damage, edema ... -
The ionic selectivity of large protein ion channels
Institut d'Estudis Catalans. Secció de Ciències i Tecnologia (2008)Large, highly conductive ion channels have a major functional role in the cell life cycle. They allow the exchange of charged and neutral solutes across the cell membrane envelope and regulate the influx of nutrients ...