Browsing FCA_Articles by Author "3e78c3eb-568e-4275-8bb6-17e71cec1b70"
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SARS-CoV-2 accessory protein 7b forms homotetramers in detergent
Surya, Wahyu; Queralt-Martin, Raquel; Mu, Yuguang; Aguilella, Vicente; Torres, Jaume BioMed Central (BMC) (2022-11)A global pandemic is underway caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 genome, like its predecessor SARS-CoV, contains open reading frames that encode accessory proteins ... -
The Complex Proteolipidic Behavior of the SARS-CoV-2 Envelope Protein Channel: Weak Selectivity and Heterogeneous Oligomerization
Surya, Wahyu; Tavares Neto, Ernesto; Sanchis, Andrea; Queralt-Martín, María; Alcaraz, Antonio; Torres, Jaume; Aguilella, Vicente Multidisciplinary Digital Publishing Institute (MDPI) (2023-08-05)The envelope (E) protein is a small polypeptide that can form ion channels in coronaviruses. In SARS coronavirus 2 (SARS-CoV-2), the agent that caused the recent COVID-19 pandemic, and its predecessor SARS-CoV-1, E protein ... -
The Cytoplasmic Domain of the SARS-CoV-2 Envelope Protein Assembles into a β-Sheet Bundle in Lipid Bilayers
Dregni, Aurelio J.; McKay, Matthew; Surya, Wahyu; Queralt-Martin, Maria; Medeiros-Silva, João; Wang, Harrison K.; Aguilella, Vicente; Torres, Jaume; Hong, Mei Elsevier (2023-01-28)The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein forms a pentameric ion channel in the lipid membrane of the endoplasmic reticulum Golgi intermediate compartment (ERGIC) of the infected ...