Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines C, O and P
Impact
![Google Scholar](/xmlui/themes/Mirage2/images/uji/logo_google.png)
![Microsoft Academico](/xmlui/themes/Mirage2/images/uji/logo_microsoft.png)
Metadata
Show full item recordcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7053
comunitat-uji-handle3:10234/8639
comunitat-uji-handle4:
INVESTIGACIONThis resource is restricted
http://dx.doi.org/10.1016/j.tet.2009.10.066 |
Metadata
Title
Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines C, O and PDate
2009Publisher
ElsevierISSN
404020Bibliographic citation
Tetrahedron, 65, 51, p. 10612-10616Type
info:eu-repo/semantics/articleAbstract
The first syntheses of the polyhydroxylated alkaloids (iminosugars) broussonetines O and P, glycosidase inhibitors of the pyrrolidine class, have been performed in a convergent, stereocontrolled way from d-serine as ... [+]
The first syntheses of the polyhydroxylated alkaloids (iminosugars) broussonetines O and P, glycosidase inhibitors of the pyrrolidine class, have been performed in a convergent, stereocontrolled way from d-serine as the chiral starting material. The synthesis of broussonetin C, a further member of this compound family, is also reported. A cross-metathesis step was one key feature of the synthesis. The versatility of the synthetic concept chosen permits the access to many members of this compound family, both natural ones and analogues thereof. © 2009 Elsevier Ltd. All rights reserved. [-]
Rights
http://rightsstatements.org/vocab/CNE/1.0/
info:eu-repo/semantics/restrictedAccess
info:eu-repo/semantics/restrictedAccess
This item appears in the folowing collection(s)
- QUIO_Articles [701]
xmlui.dri2xhtml.METS-1.0.item-elsevier-embed
![PDF](/xmlui/themes/Mirage2/images/uji/elsevier-pdf.png)