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Mortality and cardiovascular disease burden of uncontrolled diabetes in a registry-based cohort: the ESCARVAL-risk study
(BMC, 2018-09-04)
Background:
Despite the epidemiological evidence about the relationship between diabetes, mortality and cardiovascular disease, information about the population impact of uncontrolled diabetes is scarce. We aimed to ...
Poor mothers, unhealthy children: the transmission of health inequalities in the INMA study, Spain
(Oxford University Press, 2019-06)
Background
The health of pregnant women and their fetuses are especially sensitive to socioeconomic conditions. This study analyzes the impact of maternal socioeconomic status (SES), evaluated by occupation and maternal ...
Home-based inspiratory muscle training for management of older patients with heart failure with preserved ejection fraction: does baseline inspiratory muscle pressure matter?
(SAGE, 2019-05-31)
Background:
Heart failure with preserved ejection fraction is a clinical syndrome characterised by reduced exercise capacity. Some evidence has shown that a simple and home-based programme of inspiratory muscle training ...
Trastorno por déficit de atención con hiperactividad y trastorno bipolar en gemelas dicigóticas. A propósito de un caso
(Elsevier España, 2008-03)
Desde que Wozniak et al describieran una elevada incidencia de trastorno bipolar (16%) entre los niños y adolescentes diagnosticados de trastorno por déficit de atención con hiperactividad (TDAH) ha existido un interés ...
Electrophysiology of the pancreatic islet β-cell sweet taste receptor TIR3
(Springer, 2018)
Over recent years, the presence of the sweet taste receptor TIR3 in rodent and human insulin-producing pancreatic islet β-cells
was documented. The activation of this receptor by sweet-tasting sucralose mimics several ...
Estudio sobre aspectos etiológicos de la patología dual
(Sociedad Científica Española de Estudios sobre el Alcohol, el Alcoholismo y las otras Toxicomanías, 2010)
Introducción: Es importante evaluar la interacción entre los antecedentes psicopatológicos familiares (AF), la dinámica familiar (DF), los trastornos de conducta, los trastornos por uso de sustancias y los trastornos de ...
Pacientes bipolares de unidades especializadas y de centros de salud mental. ¿Se pueden comparar?
(Elsevier, 2009)
Introduction
Bipolar patients recruited for studies are usually picked from Bipolar Disorder Units, which only contain a fraction of the total population of patients with bipolar disorder. The purpose of this study was ...
Can We Treat Neuroinflammation in Alzheimer's Disease?
(MDPI, 2020-11-19)
Alzheimer’s disease (AD), considered the most common type of dementia, is characterized by a progressive loss of memory, visuospatial, language and complex cognitive abilities. In addition, patients often show comorbid ...
Intensive longitudinal modelling predicts diurnal activity of salivary alpha-amylase
(Public Library of Science, 2019)
Salivary alpha-amylase (sAA) activity has been widely used in psychological and medical
research as a surrogate marker of sympathetic nervous system activation, though its utility
remains controversial. The aim of this ...
Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice
(BioMed Central, 2016)
Background:
Synthetic zinc finger (ZF) proteins can be targeted to desired DNA sequences and are useful tools for gene therapy. We recently developed a ZF transcription repressor (ZF-KOX1) able to bind to expanded DNA ...