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JAK2 mediates lung fibrosis, pulmonary vascular remodelling and hypertension in idiopathic pulmonary fibrosis: an experimental study
(BMJ, 2018)
Background Pulmonary hypertension (PH) is a common disorder in patients with idiopathic pulmonary fibrosis (IPF) and portends a poor prognosis. Recent studies using vasodilators approved for PH have failed in improving IPF ...
Effects of Acute Ethanol Administration on Brain Oxidative Status: The Role of Acetaldehyde
(Wiley, 2019-08)
Background:
Ethanol (EtOH), one of the most widely consumed substances of abuse, can induce brain damage and neurodegeneration. EtOH is centrally metabolized into acetaldehyde, which has been shown to be responsible for ...
Percepción de los pacientes en cuanto al manejo de la fibrosis
pulmonar idiopática. Proyecto Explora-IPF
(Elsevier, 2022)
Introduction
Idiopathic pulmonary fibrosis (IPF) impacts the life of patients and their families, so it is necessary to ascertain their perception in the approach to their disease.
Methods
Observational study by means ...
Quick Recovery of Renal Alterations and Inflammatory Activation after a Marathon
(Karger Publishers, 2019)
Purpose: We evaluated the incidence of acute kidney injury in a cohort of marathon participants. Methods: We conducted a prospective observational study focused on evaluating the incidence of kidney damage after a marathon, ...
Outcome quality standards for surgery of colorectal liver metastasis
(Springer, 2020)
Purpose Liver metastases are the most common malignant solid liver lesions, approximately 40% of which stem from colorectal
tumors. Liver resection is currently the only curative treatment for colorectal cancer liver ...
Alpha-Theta effects associated with ageing during the stroop test
(Public Library of Science, 2014)
The Stroop effect is considered as a standard attentional measure to study conflict resolution in humans. The response of the brain to conflict is supposed to change over time and it is impaired in certain pathological ...
Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma
(Public Library of Science, 2014)
Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ...
An anti-interleukin-2 receptor drug attenuates thelper 1 lymphocytes-mediated inflammation in an acute model of endotoxin-induced uveitis
(Public Library of Science, 2014)
The aim of the present study was to evaluate the anti-inflammatory efficacy of Daclizumab, an anti-interleukin-2 receptor
drug, in an experimental uveitis model upon a subcutaneous injection of lipopolysaccharide into ...
Aplicación del modelo alternativo de diagnóstico de Trastorno de la Personalidad DSM-5 para valorar la evolución de una paciente adolescente: caso clínico
(Asociación Española de Psiquiatría del Niño y el Adolescente, 2016-12-07)
La quinta edición del Manual Diagnóstico y Estadístico de Trastornos Mentales, en su Sección III, presenta un modelo alternativo para el diagnóstico de los Trastornos de la Personalidad que intenta eliminar algunos de los ...
Cross-sectional analysis of the medium-term impact of bariatric surgery onpharmacological expenditure
(Elsevier, 2019)
Introduction:Obesity and associated diseases represent an important health and economic problem sincepharmacological treatment for many of these pathologies needs lifelong subsidies. Theoretically, bariatric andmetabolic ...