ListarMED_Articles por tema "Parkinson’s disease"
Mostrando ítems 1-6 de 6
-
Dopamine modulation affects the performance of parkinsonian patients in a precision motor task measured by an antropomorphic device
Elsevier (2012)Several parameters related to the timing, grip force and load force involved in a precision grasping task were studied in patients with Parkinson’s disease (PD) at different moments of medication and healthy controls, using ... -
Evidence of oligodendrogliosis in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism
Wiley (2013)Aims: Mice and nonhuman primates administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) represent elective experimental models of Parkinsonism, in which degeneration of the nigrostriatal dopaminergic pathway ... -
Functional role of Barrington’s nucleus in the micturition reflex: Relevance in the surgical treatment of Parkinson’s disease
Elsevier (2014)The pontine micturition center or Barrington’s nucleus (BN) – besides regulating micturition – co-regulates the activity of other pelvic viscera such as the colon and genitals. At present, this issue is gaining particular ... -
Metalloproteinase-9 contributes to inflammatory glia activation and nigro-striatal pathway degeneration in both mouse and monkey models of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism
Springer (2014-02)Inflammation is a predominant aspect of neurodegenerative diseases, manifested by glia activation and expression of pro-inflammatory mediators. Studies on animal models of Parkinson’s disease (PD) suggest that sustained ... -
Nigral degeneration correlates with persistent activation of cerebellar Purkinje cells in MPTP-treated monkeys
Universidad de Murcia (2012)In the present work we analyze the cerebellum of chronic parkinsonian monkeys in order to clarify whether chronic mesencephalic depletion is associated with long term activation of the cerebellar neurons in chronic ... -
ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo
Nature Publishing Group (2012)The role of microglial motility in the context of adult neurodegeneration is poorly understood. In the present work, we investigated the microanatomical details of microglia-neuron interactions in an experimental ...