ListarMED_Articles por tema "HIV"
Mostrando ítems 1-4 de 4
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ER stress in human hepatic cells treated with Efavirenz: Mitochondria again
Elsevier (2013-10)Background & Aims ER stress is associated with a growing number of liver diseases, including drug-induced hepatotoxicity. The non-nucleoside analogue reverse transcriptase inhibitor Efavirenz, a cornerstone of the ... -
Involvement of nitric oxide in the mitochondrial action of efavirenz: a differential effect on neurons and glial cells
Oxford University Press (2014-12)The anti-human immunodeficiency virus (HIV) drug efavirenz (EFV) alters mitochondrial function in cultured neurons and glial cells. Nitric oxide (NO) is a mediator of mitochondrial dysfunction associated with HIV central ... -
Mitochondrial (dys)function-a factor underlying the variability of EFV-induced hepatoxicity?
Wiley (2015-01-08)Background and PurposeThe non-nucleoside analogue reverse transcriptase inhibitor efavirenz is associated with hepatic toxicity and metabolic disturbances. Although the mechanisms involved are not clear, recent evidence ... -
Neuronal Bioenergetics and Acute Mitochondrial Dysfunction: A Clue to Understanding the Central Nervous System Side Effects of Efavirenz
Oxford University Press (2014-05)Background. Neurological pathogenesis is associated with mitochondrial dysfunction and differences in neuronal/glial handling of oxygen and glucose. The main side effects attributed to efavirenz involve the CNS, but the ...