Visualitzant MED_Articles per data de publicació
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Differential efferent projections of the anterior, posteroventral, and posterodorsal subdivisions of the medial amygdala in mice
Frontiers (2012-08-21)The medial amygdaloid nucleus (Me) is a key structure in the control of sociosexual behavior in mice. It receives direct projections from the main and accessory olfactory bulbs (AOB), as well as an important hormonal input. ... -
Gender is a major factor explaining discrepancies in eye colour prediction based on HERC2/OCA2 genotype and the IrisPlex model
Elsevier (2013)In recent years, several studies have greatly increased our understanding of the genetic basis underlying human eye colour variation. A large percentage of the eye colour diversity present in humans can already be genetically ... -
Reproducibility and validity of a food frequency questionnaire among pregnant women in a Mediterranean area
BioMed Central (2013)Background: Studies exploring the role of diet during pregnancy are still scarce, in part due to the complexity of measuring diet and to the lack of valid instruments. The aim of this study was to examine the reproducibility ... -
Alterations in energy metabolism, neuroprotection and visual signal transduction in the retina of parkinsonian, MPTP-treated monkeys
Public Library of Science (2013)Campello L, Esteve-Rudd J, Bru-Martínez R, Herrero MT, Fernández-Villalba E, et al. (2013) Alterations in Energy Metabolism, Neuroprotection and Visual Signal Transduction in the Retina of Parkinsonian, MPTP-Treated ... -
Evidence of oligodendrogliosis in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism
Wiley (2013)Aims: Mice and nonhuman primates administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) represent elective experimental models of Parkinsonism, in which degeneration of the nigrostriatal dopaminergic pathway ... -
Critical evaluation of the anatomical location of the Barrington nucleus: relevance for deep brain stimulation surgery of pedunculopontine tegmental nucleus
Elsevier (2013)Deep brain stimulation (DBS) has become the standard surgical procedure for advanced Parkinson’s disease (PD). Recently, the pedunculopontine tegmental nucleus (PPN) has emerged as a potential target for DBS in patients ... -
In vivo transcriptomic profile after a Mediterranean diet in high–cardiovascular risk patients: a randomized controlled trial
American Society for Nutrition (2013)Background: Nutrients can exert healthy effects through nutrigenomic modulation. Data are scarce concerning the in vivo effect of a sustained traditional Mediterranean diet (TMD) pattern on the whole transcriptomic ... -
Perspectives and Potential Applications of Mitochondria-Targeted Antioxidants in Cardiometabolic Diseases and Type 2 Diabetes
John Wiley & Sons (2013)There is abundant evidence to suggest that mitochondrial dysfunction is a main cause of insulin resistance and related cardiometabolic comorbidities. On the other hand, insulin resistance is one of the main characteristics ... -
Cuidado Con Las Comparaciones Indirectas: A Proposito De Los Nuevos Anticoagulantes Orales
EDICIONES DOYMA S A (2013) -
Naltrexone Reverses Ethanol-Induced Rat Hippocampal and Serum Oxidative Damage
Hindawi Publishing Corporation (2013)Naltrexone, an antagonist of 𝜇�-opioid receptors, is clinically used as adjuvant therapy of alcohol dishabituation. The aim of the present work was to test the effect of 1 mg/kg body weight of naltrexone to revert oxidative ... -
Evaluation of symptomatic drug effects in Alzheimer’s disease: strategies for prediction of efficacy in humans
Elsevier (2013)In chronic diseases such as Alzheimer's disease (AD), the arsenal of biomarkers available to determine the effectiveness of symptomatic treatment is very limited. Interpretation of the results provided in literature is ... -
Persistent phagocytic characteristics of microglia in the substantia nigra of long-term Parkinsonian macaques
Elsevier (2013)Patients with Parkinson's disease show persistent microglial activation in the areas of the brain where the degeneration of dopaminergic neurons takes place. The reason for maintaining this activated state is still unknown, ... -
Effects of pharmacological agents, sleep deprivation, hypoxia and transcranial magnetic stimulation on electroencephalographic rhythms in rodents: Towards translational challenge models for drug discovery in Alzheimer’s disease
Elsevier (2013)Different kinds of challenge can alter spontaneous ongoing electroencephalographic (EEG) rhythms in animal models, thus providing paradigms to evaluate treatment effects in drug discovery. The effects of challenges represented ... -
Maternal pre-pregnancy overweight and obesity, and child neuropsychological development: two Southern European birth cohort studies
International Epidemiological Association (2013)Background Maternal pre-pregnancy obesity may be associated with impaired infant neuropsychological development; however, there are few studies and it is unclear if reported associations are due to intrauterine ... -
Prenatal and postnatal insecticide use and infant neuropsychological development in a multicenter birth cohort study
Elsevier (2013)There is little evidence about exposure to currently used insecticides during early life periods and adverse effects on child neuropsychological development. The aim of this study is to examine the association between ... -
Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population
BioMed Central (2013-03)Background Few high penetrance genes are known in Malignant Melanoma (MM), however, the involvement of low-penetrance genes such as MC1R, OCA2, ASIP, SLC45A2 and TYR has been observed. Lately, genome-wide association ... -
Iodine Supplementation During Pregnancy and Infant Neuropsychological: INMA Mother and Child Cohort Study
Oxford University Press (2013-04)Iodine supplementation during pregnancy is a common practice in developed countries. However, scant evidence is available regarding the safety and effectiveness of maternal iodine supplementation with regard to child ... -
Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease
Wiley (2013-05-27)Octodon degus (O. degus) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, O. degus has recently been identified ... -
Electrolytic lesion of the nucleus incertus retards extinction of auditory conditioned fear
Elsevier (2013-06-15)Fear memory circuits in the brain function to allow animals and humans to recognize putative sources of danger and adopt an appropriate behavioral response; and research on animal models of fear have helped reveal the ... -
Dietary intake in pregnant women in a Spanish Mediterranean area: as good as it is supposed to be?
Cambridge University Press (2013-08)Objective To assess food and nutrient intakes and compliance with nutritional recommendations in pregnant women according to selected sociodemographic characteristics. Design Cross-sectional study based on data from the ...