Listar MED_Articles por fecha de publicación
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Influencia de la inmigración en los patrones de transmisión de la tuberculosis en Castellón (2004–2007)
Elsevier (2011)Objetivo Describir los patrones de transmisión de la tuberculosis en Castellón en un periodo de importantes cambios demográficos. Métodos Estudio prospectivo descriptivo de los pacientes con cultivo positivo en la ... -
IFN-c signaling, with the synergistic contribution of TNF-a, mediates cell specific microglial and astroglial activation in experimental models of Parkinson’s disease
Nature Publishing Group (2011)To through light on the mechanisms underlying the stimulation and persistence of glial cell activation in Parkinsonism, we investigate the function of IFN-c and TNF-a in experimental models of Parkinson’s disease and ...
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Actividad física y su relación con el estado de salud en pacientes EPOC estables
Elsevier España (Elsevier Doyma) (2011)Introducción Estudios previos han resaltado que la actividad física (AF) en la EPOC se asocia a mejor calidad de vida y menor morbimortalidad. Nuestro objetivo ha sido conocer los hábitos de AF en la vida diaria de ... -
Cladistic Analysis of Olfactory and Vomeronasal Systems
Frontiers (2011-01-26)Most tetrapods possess two nasal organs for detecting chemicals in their environment, which are the sensory detectors of the olfactory and vomeronasal systems. The seventies’ view that the olfactory system was only devoted ...
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Effects of omalizumab in Aspergillus-associated airway disease
Georg Thieme Verlag (2011-03)The clinical spectrum of Aspergillus-associated airway diseases (AAAD) includes Aspergillus-induced asthma, allergic bronchopulmonary aspergillosis (ABPA) and bronchocentric granulomatosis. Corticosteroids are almost ...
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Amygdaloid projections to the ventral striatum in mice: direct and indirect chemosensory inputs to the brain reward system
Frontiers (2011-08-22)Rodents constitute good models for studying the neural basis of sociosexual behavior. Recent findings in mice have revealed the molecular identity of the some pheromonal molecules triggering intersexual attraction. However, ...
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Interobserver discrepancy in liver fibrosis using transient elastography
John Wiley & Sons (2012)Transient elastography is a useful method to assess liver fibrosis, but uncertainties still exist regarding reliability and reproducibility of the technique. We aimed to improve knowledge on interobserver variability with ...
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Nigral degeneration correlates with persistent activation of cerebellar Purkinje cells in MPTP-treated monkeys
Universidad de Murcia (2012)In the present work we analyze the cerebellum of chronic parkinsonian monkeys in order to clarify whether chronic mesencephalic depletion is associated with long term activation of the cerebellar neurons in chronic ...
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ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo
Nature Publishing Group (2012)The role of microglial motility in the context of adult neurodegeneration is poorly understood. In the present work, we investigated the microanatomical details of microglia-neuron interactions in an experimental ...
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Dopamine modulation affects the performance of parkinsonian patients in a precision motor task measured by an antropomorphic device
Elsevier (2012)Several parameters related to the timing, grip force and load force involved in a precision grasping task were studied in patients with Parkinson’s disease (PD) at different moments of medication and healthy controls, using ...
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CCL2-Expressing astrocytes mediate the extravasation of T lymphocytes in the brain. Evidence from patients with glioma and experimental models in vivo
Public Library of Science (2012)CCL2 is a chemokine involved in brain inflammation, but the way in which it contributes to the entrance of lymphocytes in the parenchyma is unclear. Imaging of the cell type responsible for this task and details on how ...
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Parkinson’s disease and autophagy
Hindawi Publishing Corporation (2012)It is generally accepted that a correlation between neurodegenerative disease and protein aggregation in the brain exists; however, a causal relationship has not been elucidated. In neurons, failure of autophagy may result ...
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7-Nitroindazole down-regulates dopamine/DARPP-32 signaling in neostriatal neurons in a rat model of Parkinson's disease
Elsevier (2012)Neuronal nitric oxide synthase (nNOS) is involved in the regulation of diverse intracellular messenger systems in the brain. Nitric Oxide (NO) contributes to inducing signaling cascades that involve a complex pattern of ...
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Distribution and targets of the relaxin-3 innervation of the septal area in the rat
Wiley-Blackwell (2012)Neural tracing studies have revealed that the rat medial and lateral septum are targeted by ascending projections from the nucleus incertus, a population of tegmental GABA neurons. These neurons express the relaxin-family ...
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Hepatitis C virus co-infection and sexual risk behaviour are associated with a high homocysteine serum level in HIV-infected patients
EMH Swiss Medical Publishers (2012-01)BACKGROUND AND AIMS: A better understanding of the relationship of homocysteine with cardiovascular risk factors is needed. The objectives of this study were to assess the serum level of homocysteine in HIV-infected patients ...
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Lesions of the dopaminergic innervation of the nucleus accumbens medial shell delay the generation of preference for sucrose, but not of sexual pheromones
Elsevier (2012-01)Male sexual pheromones are rewarding stimuli for female mice, able to induce conditioned place preference. To test whether processing these natural reinforcing stimuli depends on the dopaminergic innervation of the nucleus ...
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Differential hippocampal response to chronic alcohol consumption of young adult and mature adult rats
Oxford University Press (2012-05)AIMS Early ethanol consumption could be a risk factor for young brain integrity and its maturation, and also for the development of addictive behaviors in adulthood. Neuronal nitric oxide synthase (nNOS) expressing neurons ...
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Adaptive function and brain evolution
Frontiers (2012-05-29)
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IRS-2 deficiency impairs NMDA receptor-dependent long-term potentiation
Oxford University Press (2012-08)The beneficial effects of insulin and insulin-like growth factor I on cognition have been documented in humans and animal models. Conversely, obesity, hyperinsulinemia, and diabetes increase the risk for neurodegenerative ...
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Administration of docosahexaenoic acid before birth and until aging decreases kainate-induced seizures in adult zebrafish
Elsevier (2012-08-01)Docosahexaeonic acid (DHA) is the final compound in the omega-3 polyunsaturated fatty acids (PUFA) synthetic pathway and the most abundant PUFA found in the brain. DHA plays an essential role in the development of the ...
