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Mostrando ítems 259-278 de 662

    • openAccess   Fisiopatología renal y mecanismos farmacológicos de nefroprotección 

      Górriz, José Luis; Górriz-Zambrano, Carmen; Pallarés-Carratalá, Vicente Elsevier (2023-06)
      Son varios los factores de riesgo que pueden afectar la progresión de la enfermedad renal crónica (ERC). La hipertensión arterial, la proteinuria, la obesidad, la hipertensión intraglomerular, el tabaco y el control ...

    • openAccess   Focal Lesions within the ventral striato-pallidum abolish attraction for male chemosignals in female mice 

      Agustín-Pavón, Carmen; Martinez-Garcia, Fernando; Lanuza, Enrique Elsevier (2014-02)
      In rodents, socio-sexual behaviour is largely mediated by chemosensory cues, some of which are rewarding stimuli. Female mice display an innate attraction towards male chemosignals, dependent on the vomeronasal system. ...

    • openAccess   Folic Acid Supplementation during Pregnancy and Its Association with Telomere Length in Children at Four Years: Results from the INMA Birth Cohort Study 

      Petermann Rocha, Fanny; Valera-Gran, Desirée; Prieto Botella, Daniel; Martens, Dries S; González Palacios, Sandra; Riaño-Galan, Isolina; Murcia, Mario; Irizar Loibide, Amaia; Julvez, Jordi; Santa-Marina, Loreto; Tardón, Adonina; Sunyer, Jordi; Vioque, Jesus; Nawrot, Tim; Navarrete-Muñoz, Eva María MDPI (2023)
      This study examined the association between folic acid supplements (FAs) during different periods of pregnancy and offspring telomere length (TL) at age four in 666 children from the INMA study. FAs were self-reported ...

    • closedAccess   Fos response of the tail of the ventral tegmental area to food restriction entails a prediction error processing 

      Sánchez-Catalán, María José; Barrot, Michel Elsevier (2022-05-03)
      The tail of the ventral tegmental area (tVTA) or rostromedial tegmental nucleus (RMTg) receives lateral habenula inputs and projects heavily to midbrain dopamine neurons. Midbrain dopamine and lateral habenula neurons ...

    • closedAccess   Frailty as a predictor of short-and long-term mortality in critically ill older medical patients 

      Silva-Obregón, J.Alberto; Quintana Díaz, Victor Manuel; Saboya-Sánchez, Sonia; Marian-Crespo, Carlos; Romera-Ortega, M. Ángel; Chamorro-Jambrina, Carlos; Estrella Alonso, Alfonso; Andrés Esteban, Eva María Elsevier (2019-01-01)
      Purpose Frailty is a common condition among critically ill patients. Usually evaluated in a mixed population of medical, cardiac and surgical patients, we aimed to assess the impact of frailty on short- and long-term ...

    • openAccess   From back to front: A functional model for the cerebellar modulation in the establishment of conditioned preferences for cocaine‐related cues 

      Gil-Miravet, Isis; Melchor Eixea, Ignasi; Arias-Sandoval, Edgar; Vasquez‐Celaya, Lizbeth; Olucha-Bordonau, Francisco E; MIQUEL, MARTA Wiley (2019)
      It is now increasingly clear that the cerebellum may modulate brain functions altered in drug addiction. We previously demonstrated that cocaine‐induced conditioned preference increased activity at the dorsal posterior ...

    • openAccess   From sexual attraction to maternal aggression: When pheromones change their behavioural significance 

      Martín Sánchez, Ana; McLean, Lynn; Beynon, Robert J.; Hurst, Jane L.; Ayala Gallego, Guillermo; Lanuza, Enrique; Martinez-Garcia, Fernando Elsevier (2015-02)
      This article is part of a Special Issue “Chemosignals and Reproduction”. This paper reviews the role of chemosignals in the socio-sexual interactions of female mice, and reports two experiments testing the role of ...

    • closedAccess   Functional role of Barrington’s nucleus in the micturition reflex: Relevance in the surgical treatment of Parkinson’s disease 

      Herrero Ezquerro, María Trinidad; Blanco, Lisette; Ros Gómez, Carmen María; Tarragon Cros, Ernesto; Fernández Villalba, Emiliano Elsevier (2014)
      The pontine micturition center or Barrington’s nucleus (BN) – besides regulating micturition – co-regulates the activity of other pelvic viscera such as the colon and genitals. At present, this issue is gaining particular ...

    • openAccess   GABAergic Neurons in the Rat Medial Septal Complex Express Relaxin-3 Receptor (RXFP3) mRNA 

      Albert Gasco, Hector; Ma, Sherie; Ros Bernal, Francisco; Sánchez-Pérez, Ana María; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2018-01-17)
      The medial septum (MS) complex modulates hippocampal function and related behaviors. Septohippocampal projections promote and control different forms of hippocampal synchronization. Specifically, GABAergic and cholinergic ...

    • closedAccess   Gender and eye colour prediction discrepancies: A reply to criticisms (letter) 

      Martinez-Cadenas, Conrado; Peña Chilet, María; Llorca-Cardeñosa, Marta J.; Cervera, Raimundo; Ibarrola-Villava, Maider; Ribas, Gloria Elsevier (2014)
      Letter to the editor: In a letter published in this same issue, Liu et al. reply to a recently published article by us contesting the main conclusion of our original paper, namely, that gender is a factor that contributes to ...

    • openAccess   Gender differences in the diagnosis of dyslipidemia: ESCARVAL-GENERO 

      Soriano Maldonado, Cristina; Lopez-Pineda, Adriana; Orozco-Beltran, Domingo; QUESADA, JOSE ANTONIO; Alfonso Sanchez, Jose; Pallarés-Carratalá, Vicente; Navarro Pérez, Jorge; Gil-Guillen, Vicente F.; Martin-Moreno, Jose M.; Carratala-Munuera, Concepcion MDPI (2021)
      Evidence shows that objectives for detecting and controlling dyslipidemia are not being effectively met, and outcomes differ between men and women. This study aimed to assess gender-related differences in diagnostic inertia ...

    • closedAccess   Gender differences in the neurotoxicity of metals in children 

      Llop, Sabrina; López Espinosa, María José; Rebagliato, Marisa; Ballester, Ferran Elsevier (2013-09)
      Gender-related differences in susceptibility to chemical exposure to neurotoxicants have not received sufficient attention. Although a significant number of epidemiological studies on the neurodevelopmental effects of metal ...

    • openAccess   Gender Inequalities in Diagnostic Inertia around the Three Most Prevalent Cardiovascular Risk Studies: Protocol for a Population-Based Cohort Study 

      Carratala-Munuera, Concepcion; López Pineda, Adriana; Orozco-Beltran, Domingo; QUESADA, JOSE ANTONIO; Alfonso Sanchez, Jose; Pallarés-Carratalá, Vicente; Soriano Maldonado, Cristina; Navarro Pérez, Jorge; Gil-Guillén, Vicente F; Martin-Moreno, Jose M. MDPI (2021)
      Evidence shows that objectives for detecting and controlling cardiovascular risk factors are not being effectively met, and moreover, outcomes differ between men and women. This study will assess the gender-related differences ...

    • openAccess   Gender is a major factor explaining discrepancies in eye colour prediction based on HERC2/OCA2 genotype and the IrisPlex model 

      Martinez-Cadenas, Conrado; Peña Chilet, María; Ibarrola-Villava, Maider; Ribas, Gloria Elsevier (2013)
      In recent years, several studies have greatly increased our understanding of the genetic basis underlying human eye colour variation. A large percentage of the eye colour diversity present in humans can already be genetically ...

    • openAccess   Genetic 3’UTR variation is associated with human pigmentation characteristics and sensitivity to sunlight 

      Hernando, Barbara; Peña-Chilet, Maria; Ibarrola-Villava, Maider; Martín González, Manuel; Gómez Fernández, Cristina; Ribas, Gloria; Martinez-Cadenas, Conrado Wiley (2017-10)
      Sunlight exposure induces signalling pathways leading to the activation of melanin synthesis and tanning response. MicroRNAs (miRNAs) can regulate the expression of genes involved in pigmentation pathways by binding to the ...

    • openAccess   Genetic determinants of freckle occurrence in the Spanish population: Towards ephelides prediction from human DNA samples 

      Hernando, Barbara; Ibáñez Gual, Maria Victoria; Deserio Cuesta, Julio Alberto; Soria Navarro, Raquel; Vilar Sastre, Inca; Martinez-Cadenas, Conrado Elsevier (2018-03)
      Prediction of human pigmentation traits, one of the most differentiable externally visible characteristics among individuals, from biological samples represents a useful tool in the field of forensic DNA phenotyping. ...

    • openAccess   Genetic Load of SARS-CoV-2 in Aerosols Collected in Operating Theaters 

      Barberá-Riera, María; Porru, Simona; Barneo-Muñoz, Manuela; Villasante Ferrer, Andrea; Carrasco, Paula; de Llanos, Rosa; Llueca, Antoni; Delgado-Saborit, Juana Maria; COVID-Lap Working Group American Society for Microbiology (2022-09-14)
      After the outbreak of COVID-19, additional protocols have been established to prevent the transmission of the SARS-CoV-2 from the patient to the health personnel and vice versa in health care settings. However, in the case ...

    • openAccess   Genetic variants associated with skin photosensitivity in a southern European population from Spain 

      Hernando, Barbara; Sanz-Page, Elena; PITARCH BORT, GERARD; Mahiques, Laura; Valcuende-Cavero, Francisca; Martinez-Cadenas, Conrado Wiley (2018)
      Background/Purpose: Recent GWAS studies, mostly performed in populations of North European origin, have identified the genetic loci associated with pigmentation, sun sensitivity, freckling and skin cancer ...

    • openAccess   Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population 

      Peña Chilet, María; Blanquer Maceiras, Maite; Ibarrola-Villava, Maider; Martinez-Cadenas, Conrado; Martín González, Manuel; Gómez Fernández, Cristina; Mayor, Matías; Avilés, Juan Antonio; Lluch , Ana; Ribas, Gloria BioMed Central (2013-03)
      Background Few high penetrance genes are known in Malignant Melanoma (MM), however, the involvement of low-penetrance genes such as MC1R, OCA2, ASIP, SLC45A2 and TYR has been observed. Lately, genome-wide association ...

    • openAccess   Glioblastoma Therapy: Past, Present and Future 

      OBRADOR, ELENA; Moreno Murciano, Paz; Oriol-Caballo, María; López Blanch, Rafael; Pineda, Begoña; Gutierrez Arroyo, Julia Lara; Loras Monfort, Alba; Gonzalez Bonet, Luis Germán; Martinez-Cadenas, Conrado; Estrela, Jose M.; Marques-Torrejon, Maria Angeles Multidisciplinary Digital Publishing Institute (MDPI) (2024-03-01)
      Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer. Although great efforts have been made by clinicians and researchers, no significant improvement in survival has been achieved since the ...