Listar MED_Articles por idioma "eng"
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2-Methyl-6-(phenylethynyl)pyridine Hydrochloride Modulates Metabotropic Glutamate 5 Receptors Endogenously Expressed in Zebrafish Brain
American Chemical Society (2016-12-21)Due to phylogenetic proximity to the human, zebrafish has been recognized as a reliable model to study Alzheimer’s disease (AD) and other central nervous system disorders. Furthermore, metabotropic glutamate receptors have ... -
7-Nitroindazole down-regulates dopamine/DARPP-32 signaling in neostriatal neurons in a rat model of Parkinson's disease
Elsevier (2012)Neuronal nitric oxide synthase (nNOS) is involved in the regulation of diverse intracellular messenger systems in the brain. Nitric Oxide (NO) contributes to inducing signaling cascades that involve a complex pattern of ... -
A cardiovascular educational intervention for primary care professionals in Spain: positive impact in a quasi-experimental study
Royal College of General Practitioners (2015-01-01)Background Routine general practice data collection can help identify patients at risk of cardiovascular disease. Aim To determine whether a training programme for primary care professionals improves the recording of ... -
A Case of Urethrocutaneous Fistula Following a Transobturator Tape Procedure for Stress Urinary Incontinence
iMedpub (2016-03)The transobturator tape procedure (TOT) is a highly effective technique used to resolve cases of female stress urinary incontinence and is a safe procedure with relatively few per-operative ... -
A case–control study to assess the effectiveness of pertussis vaccination during pregnancy on newborns, Valencian community, Spain, 1 March 2015 to 29 February 2016
European Centre for Disease Prevention and Control (ECDC) (2017-06)In the Valencian Community (Spain), the programme of maternal pertussis vaccination during pregnancy started in January 2015. The objective of this study was to estimate in this region the vaccine effectiveness (VE) in ... -
A ciliopathy complex builds distal appendages to initiate ciliogenesis
Rockefeller University Press (2021-07-09)Cells inherit two centrioles, the older of which is uniquely capable of generating a cilium. Using proteomics and superresolved imaging, we identify a module that we term DISCO (distal centriole complex). The DISCO components ... -
A Critical Period for Prefrontal Network Configurations Underlying Psychiatric Disorders and Addiction
Frontiers Media (2020-04-07)The medial prefrontal cortex (mPFC) has been classically defined as the brain region responsible for higher cognitive functions, including the decision-making process. Ample information has been gathered during the last ... -
A critical review of the epidemiological evidence of effects of air pollution on dementia, cognitive function and cognitive decline in adult population
Elsevier (2021)Dementia is arguably the most pressing public health challenge of our age. Since dementia does not have a cure,identifying risk factors that can be controlled has become paramount to reduce the personal, societal and ... -
A Fast 0.5 T Prepolarizer Module for Preclinical Magnetic Resonance Imaging
IEEE (2021-05-17)We present a magnet and high power electronics for Prepolarized Magnetic Resonance Imaging (PMRI) in a home-made, special-purpose preclinical system designed for simultaneous visualization of hard and soft biological ... -
A genome-wide association study of attention function in a population-based sample of children
Public Library of Science (2016)Background Attention function filters and selects behaviorally relevant information. This capacity is impaired in some psychiatric disorders and has been proposed as an endophenotype for Attention-Deficit/Hyperactivity ... -
A Music-Mediated Language Learning Experience: Students’ Awareness of Their Socio-Emotional Skills
Frontiers Media (2019-10-04)In a society where mobility, globalization and contact with people from other cultures have become its distinctive traits, the enhancement of plurilingualism and intercultural understanding should be of the utmost concern. ... -
A new portrait by Géricault
Elsevier (2021-02) -
A radiologic-laparoscopic model to predict suboptimal (or complete and optimal) debulking surgery in advanced ovarian cancer: a pilot study
Dove (2019-05)Introduction: Medical models assist clinicians in making diagnostic and prognostic decisions in complex situations. In advanced ovarian cancer, medical models could help prevent unnecessary exploratory surgery. We designed ... -
A Strategy for Magnetic and Electric Stimulation to Enhance Proliferation and Differentiation of NPCs Seeded over PLA Electrospun Membranes
MDPI (2022-11)Neural progenitor cells (NPCs) have been shown to serve as an efficient therapeutic strategy in different cell therapy approaches, including spinal cord injury treatment. Despite the reported beneficial effects of NPC ... -
A systematic review of neurodevelopmental effects of prenatal and postnatal organophosphate pesticide exposure
Elsevier (2014-10)Agricultural and residential use of organophosphate (OP) pesticides has increased in recent decades after banning some persistent pesticides. Although there is evidence of the effects of OPs on neurodevelopment and behaviour ... -
AAV delivery of shRNA against IRS1 in GABAergic neurons in rat hippocampus impairs spatial memory in females and male rats
Springer (2020-11-27)Brain insulin resistance is a major factor leading to impaired cognitive function and it is considered as the onset of Alzheimer´s disease. Insulin resistance is intimately linked to inflammatory conditions, many studies ... -
Abacavir induces platelet-endothelium interactions by interfering with purinergic signalling: A step from inflammation to thrombosis
Elsevier (2017-05)The controversy connecting Abacavir (ABC) with cardiovascular disease has been fuelled by the lack of a credible mechanism of action. ABC shares structural similarities with endogenous purines, signalling molecules capable ... -
Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease
Elsevier (2020)Parkinson's disease is a neurodegenerative disorder partly caused by the loss of the dopamine neurons of the nigrostriatal pathway. It is accompanied by motor as well as non-motor symptoms, including pain and depression. ... -
Abscisic Acid Supplementation Rescues High Fat Diet-Induced Alterations in Hippocampal Inflammation and IRSs Expression
Springer (2018)Accumulated evidence indicates that neuroinflammation induces insulin resistance in the brain. Moreover, both processes are intimately linked to neurodegenerative disorders, including Alzheimer’s disease. Potential mechanisms ... -
Abscisic acid, a promising therapeutic molecule to prevent Alzheimer’s and neurodegenerative diseases
Medknow Publications (2020)