Browsing MED_Articles by Author "deec0466-225b-44f2-8cf2-1f0d5f942e60"
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Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex
Navarro Sánchez, Mónica; Gil-Miravet, Isis; Montero Caballero, Daniel; Bathgate, Ross A. D.; Hossain, Mohammed Akhter; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Elsevier (2024-07)The retrosplenial cortex (RSC) plays a central role in processing contextual fear conditioning. In addition to corticocortical and thalamocortical projections, the RSC receives subcortical inputs, including a substantial ... -
Noncovalent Peptide Stapling Using Alpha-Methyl-l-Phenylalanine for α-Helical Peptidomimetics
Bathgate, Ross A. D.; Praveen, Praveen; Sethi, Ashish; Dhingra, Rishi R.; Kocan, Martina; Ou, Qinghao; Valkovic, Adam L.,; Gil-Miravet, Isis; Navarro Sánchez, Mónica; Olucha-Bordonau, Francisco E; Gundlach, Andrew Lawrence; Rosengren, K. Johan; Dutschmann, Mathias; Hossain, Mohammed Akhter American Chemical Society (2023-08-20)Peptides and peptidomimetics are attractive drug candidates because of their high target specificity and low-toxicity profiles. Developing peptidomimetics using hydrocarbon (HC)-stapling or other stapling strategies has ... -
Nucleus incertus projections to rat medial septum and entorhinal cortex: rare collateralization and septal-gating of temporal lobe theta rhythm activity
Gil-Miravet, Isis; Nuñez Molina, Angel; Navarro Sánchez, Mónica; Castillo-Gómez, Esther; Ros, Francisco; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Springer (2023)Nucleus incertus (NI) neurons in the pontine tegmentum give rise to ascending forebrain projections and express the neuropeptide relaxin-3 (RLN3) which acts via the relaxin-family peptide 3 receptor (RXFP3). Activity in ... -
Patrones de colateralización de los núcleos del rafe y del núcleo incertus al sistema septo-hipocámpico
Navarro Sánchez, Mónica; Gil-Miravet, Isis; Montero Caballero, Daniel; Lassili, Chaima; Es-Safi, Soukaina; Olucha-Bordonau, Francisco E Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2023)El núcleo incertus (NI), rico en relaxina 3 (rlN3), y los núcleos del rafe, ricos en serotonina (5ht), son unidades modulares de la línea media del tronco cerebral que influyen en diversas funciones cerebrales, entre ... -
Postnatal development of the relaxin-3 innervation of the rat medial septum
ROS, FRANCISCO; Gil-Miravet, Isis; Lucerón Morales, Jorge; Navarro Sánchez, Mónica; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2023)Introduction: The septal area provides a rich innervation to the hippocampus regulating hippocampal excitability to different behavioral states and modulating theta rhythmogenesis. However, little is known about the ... -
La proyección de Relaxina-3 sobre centros serotoninérgicos en el cerebro de la rata
Montero Caballero, Daniel; Navarro Sánchez, Mónica; Gil-Miravet, Isis; Olucha-Bordonau, Francisco E Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2023)La modulación de los sistemas cognitivos y emocionales dependen de una serie de conexiones ascendentes entre las que se encuentran las conexiones seroto- ninérgicas (5ht) y también las peptidérgicas. La Relaxina-3 ... -
Some key parameters in contextual fear conditioning and extinction in adult rats
Navarro Sánchez, Mónica; Gil-Miravet, Isis; Montero Caballero, Daniel; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Elsevier (2024-03-28)Contextual fear conditioning is a behavioral paradigm used to assess hippocampal-dependent memory in experimental animals. Perception of the context depends on activation of a distinct population of neurons in the hippocampus ...