Browsing MED_Articles by Author "dd4c75f7-622b-4037-b654-c595260f2165"
Now showing items 1-9 of 9
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Characterization of serum proteins attached to distinct sol–gel hybrid surfaces
Gomes, Nuno; Romero-Gavilán, Francisco J; Sánchez-Pérez, Ana María; GURRUCHAGA, MARILO; Azkargorta, Mikel; Elortza, Felix; Ibáñez, Maria; Iloro, Ibon; Suay, Julio; Goñi, Isabel Wiley (2017-07)The success of a dental implant depends on its osseointegration, an important feature of the implant biocompatibility. In this study, two distinct sol–gel hybrid coating formulations [50% methyltrimethoxysilane: 50% ... -
Complement proteins regulating macrophage polarisation on biomaterials
Gomes, Nuno; Romero-Gavilán, Francisco J; Zhang, Yiyue; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Martín de Llano, J. J.; GURRUCHAGA, MARILO; Goñi, Isabel; van den Beucken, J.J.J.P.; Suay, Julio Elsevier (2019-09-01)One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct ... -
Evaluation of the inflammatory responses to sol–gel coatingswith distinct biocompatibility levels
Cerqueira, Andreia; Araújo-Gomes, Nuno; Zhang, Yang; van den Beucken, Jeroen; Martínez Ramos, Cristina; ozturan, seda; Izquierdo Escrig, Raul; Muriach, Maria; Romero Cano, Ricard; Baliño, Pablo; Romero-Gavilán, Francisco J John Wiley and Sons (2021-02-20)The immune system plays a crucial role in determining the implantation outcome, and macrophages are in the frontline of the inflammatory processes. Further, cellular oxidative stress resulting from the material recognition ... -
Osseointegration mechanisms: a proteomic approach
Gomes, Nuno; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Sánchez-Pérez, Ana María; Azkargorta, Mikel; Elortza, Felix; Martín de Llano, J.J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer-Verlag (2018-03)The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ... -
Osteointegración de implantes de titanio con superficies activas. Un estudio proteómico
Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Ediciones Peldaño (2017-12)Titanium is a biomaterial largely used on dental implant manufacturing. However, as a consequence of its intrinsically low bioactivity, the development of distinct superficial treatments in order to enhance its ... -
Proteome analysis of human serum proteins adsorbed onto different titanium surfaces used in dental implants
Romero-Gavilán, Francisco J; Gomes, N. C.; Ródenas, Joaquin; Sánchez, Ana; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; García-Arnáez, Iñaki; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Taylor & Francis (2017)Titanium dental implants are commonly used due to their biocompatibility and biochemical properties; blasted acid-etched Ti is used more frequently than smooth Ti surfaces. In this study, physico-chemical characterisation ... -
Proteomic analysis of silica hybrid sol-gel coatings: a potential tool for predicting the biocompatibility of implants in vivo
Romero-Gavilán, Francisco J; Sánchez-Pérez, Ana María; Gomes, Nuno; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; Gurruchaga, Marilo; Goñi, Isabel; Suay, Julio Taylor & Francis (2017)The interactions of implanted biomaterials with the host organism determine the success or failure of an implantation. Normally, their biocompatibility is assessed using in vitro tests. Unfortunately, in vitro and in vivo ... -
Silica-gelatin hybrid sol-gel coatings: A proteomic study with biocompatibility implications
Gomes, Nuno; Romero-Gavilán, Francisco J; Lara, Irene; Elortza, Felix; Azkargorta, Mikel; Lloro, Ibon; Ibáñez, Maria; Martín de Llano, J. J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio; Sánchez-Pérez, Ana María Wiley (2018-05)Osseointegration, including the foreign body reaction to biomaterials, is an immune‐modulated, multifactorial, and complex healing process in which various cells and mediators are involved. The buildup of the osseointegration ... -
The effect of calcium–magnesium mixtures in sol–gel coatings on bone tissue regeneration
Cerqueira, Andreia; García-Arnáez, Iñaki; Muriach, Maria; Azkargorta, Mikel; Elortza, Felix; Izquierdo, Raúl; Romero-Gavilán, Francisco J; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Royal Society of Chemistry (2022)Calcium and magnesium are two elements essential for bone structure and metabolism. However, their synergistic or competitive effects on bone regeneration are often overlooked during biomaterial development. We examined ...