Browsing MED_Articles by Author "ae9271cd-0a9e-41cd-8fd3-6ecc31f02d99"
Now showing items 1-9 of 9
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Acute oral administration of low doses of methylphenidate targets calretinin neurons in the rat septal area
García Avilés, Álvaro; Albert Gasco, Hector; Arnal Vicente, Isabel; Elhajj, Ebtisam; Sanjuán, Julio; Sánchez-Pérez, Ana María; Olucha-Bordonau, Francisco E Frontiers Media (2015)Methylphenidate (MPD) is a commonly administered drug to treat children suffering from attention deficit hyperactivity disorder (ADHD). Alterations in septal driven hippocampal theta rhythm may underlie attention deficits ... -
Central relaxin-3 receptor (RXFP3) activation impairs social recognition and modulates ERK-phosphorylation in specific GABAergic amygdala neurons
Albert Gasco, Hector; Sánchez-Sarasúa, Sandra; Ma, Sherie; García Díaz, Cristina; Gundlach, Andrew Lawrence; Sánchez-Pérez, Ana María; Olucha-Bordonau, Francisco E Springer (2019-01)In mammals, the extended amygdala is a neural hub for social and emotional information processing. In the rat, the extended amygdala receives inhibitory GABAergic projections from the nucleus incertus (NI) in the pontine ... -
Central relaxin-3 receptor (RXFP3) activation increases ERK phosphorylation in septal cholinergic neurons and impairs spatial working memory.
Albert Gasco, Hector; García Avilés, Álvaro; Moustafa, S.; Sánchez-Sarasúa, Sandra; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E; Sánchez-Pérez, Ana María Springer (2016-05-05)The medial septum/diagonal band (MS/DB) is a relay region connecting the hypothalamus and brainstem with the hippocampus, and both the MS/DB and dorsal/ventral hippocampus receive strong topographic GABA/peptidergic ... -
GABAergic Neurons in the Rat Medial Septal Complex Express Relaxin-3 Receptor (RXFP3) mRNA
Albert Gasco, Hector; Ma, Sherie; Ros Bernal, Francisco; Sánchez-Pérez, Ana María; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2018-01-17)The medial septum (MS) complex modulates hippocampal function and related behaviors. Septohippocampal projections promote and control different forms of hippocampal synchronization. Specifically, GABAergic and cholinergic ... -
Involvement of the Nucleus Incertus and Relaxin-3/RXFP3 Signaling System in Explicit and Implicit Memory
Gil-Miravet, Isis; Mañas-Ojeda, Aroa; Ros Bernal, Francisco; Castillo-Gómez, Esther; Albert Gasco, Hector; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2021-03-18)Telencephalic cognitive and emotional circuits/functions are strongly modulated by subcortical inputs. The main focus of past research on the nature of this modulation has been on the widespread monoamine projections to ... -
MAP/ERK Signaling in Developing Cognitive and Emotional Function and Its Effect on Pathological and Neurodegenerative Processes
Albert Gasco, Hector; Ros, Francisco; Castillo-Gómez, Esther; Olucha-Bordonau, Francisco E MDPI (2020-06-23)The signaling pathway of the microtubule-associated protein kinase or extracellular regulated kinase (MAPK/ERK) is a common mechanism of extracellular information transduction from extracellular stimuli to the intracellular ... -
Modulation of forebrain function by nucleus incertus and relaxin-3/RXFP3 signaling
Olucha-Bordonau, Francisco E; Albert Gasco, Hector; Ros Bernal, Francisco; Rytova, Valeria; Ong-Pålsson, Emma K. E.; Ma, Shuai; Sánchez-Pérez, Ana María; Gundlach, Andrew Lawrence Wiley (2018)The nucleus incertus (NI) in the pontine tegmentum sends ascending projections to the midbrain, hypothalamus, amygdala, basal forebrain, hippocampus, and prefrontal cortex, and has a postulated role in modulating several ... -
Nucleus incertus ablation disrupted conspecific recognition and modified immediate early gene expression patterns in ‘social brain’ circuits of rats
García Díaz, Cristina; Sánchez-Catalán, María José; Castro-Salazar, E.; García Avilés, Álvaro; Albert Gasco, Hector; Sánchez-Sarasúa, Sandra; Sánchez-Pérez, Ana María; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Elsevier (2019-01-01)Social interaction involves neural activity in prefrontal cortex, septum, hippocampus, amygdala and hypothalamus. Notably, these areas all receive projections from the nucleus incertus (NI) in the pontine tegmentum. ... -
Relaxin-3 Innervation From the Nucleus Incertus to the Parahippocampal Cortex of the Rat
García Díaz, Cristina; Gil-Miravet, Isis; Albert Gasco, Hector; Mañas-Ojeda, Aroa; Ros Bernal, Francisco; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2021)Spatial learning and memory processes depend on anatomical and functional interactions between the hippocampus and the entorhinal cortex. A key neurophysiological component of these processes is hippocampal theta rhythm, ...