• openAccess   New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration 

      Kaneko, Naoko; Herranz-Pérez, Vicente; Otsuka, Takanobu; Sano, H.; Ohno, N.; Omata, T.; Nguyen, Huy Bang; Thai, T.Q.; Nambu, A.; Kawaguchi, Yuki; García-Verdugo, Jose Manuel; Sawamoto, Kazunobu American Association for the Advancement of Science (2018)
      After brain injury, neural stem cell–derived neuronal precursors (neuroblasts) in the ventricular-subventricular zone migrate toward the lesion. However, the ability of the mammalian brain to regenerate neuronal ...
    • openAccess   Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury 

      Jinnou, Hideo; Sawada, Masato; Kawase, Koya; Kaneko, Naoko; Herranz-Pérez, Vicente; Miyamoto, Takuya; Kawaue, Takumi; Miyata, Takaki; Tabata, Yasuhiko; Akaike, Toshihiro; García-Verdugo, Jose Manuel; Ajioka, Itsuki; Saitoh, Shinji; Sawamoto, Kazunobu Elsevier (2018-01-04)
      Radial glia (RG) are embryonic neural stem cells (NSCs) that produce neuroblasts and provide fibers that act as a scaffold for neuroblast migration during embryonic development. Although they normally disappear soon after ...
    • openAccess   Unique Organization of the Nuclear Envelope in the Post-natal Quiescent Neural Stem Cells 

      Cebrián-Silla, Arantxa; Alfaro-Cervelló, Clara; Herranz-Pérez, Vicente; Kaneko, Naoko; Park, Dae Hwi; Sawamoto, Kazunobu; Alvarez-Buylla, Arturo; Lim, Daniel A.; García-Verdugo, Jose Manuel Elsevier (Cell Press) (2017)
      Neural stem cells (B1 astrocytes; NSCs) in the adult ventricular-subventricular-zone (V-SVZ) originate in the embryo. Surprisingly, recent work has shown that B1 cells remain largely quiescent. They are reactivated postnatally ...