Browsing MED_Articles by Author "99e16739-a8c0-49f2-9e0a-45bbc1f84742"
Now showing items 1-11 of 11
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Becoming stressed: Does the age matter? Reviewing the neurobiological and socio-affective effects of stress throughout the lifespan
Mañas-Ojeda, Aroa; Ros, Francisco; Olucha-Bordonau, Francisco E; Castillo-Gómez, Esther MDPI (2020-08-13)Social and affective relations occur at every stage of our lives. Impairments in the quality of this “social world” can be exceptionally detrimental and lead to psychopathology or pathological behavior, including ... -
Effects of Dopamine on the Immature Neurons of the Adult Rat Piriform Cortex
Coviello, Simona; Montes Cebrián, Yaiza; Castillo-Gómez, Esther; Nacher, Juan Frontiers Media (2020-10-06)The layer II of the adult piriform cortex (PCX) contains a numerous population of immature neurons. Interestingly, in both mice and rats, most, if not all, these cells have an embryonic origin. Moreover, recent studies ... -
Impact of stress on inhibitory neuronal circuits, our tribute to Bruce McEwen
Perez-Rando, Marta; Carceller, Hector; Castillo-Gómez, Esther; Bueno-Fernández, Clara; García-Mompó, Clara; Gilabert-Juan, Javier; Guirado, Ramón; Pesarico, Ana Paula; Nacher, Juan Elsevier (2022)This manuscript is dedicated to the memory of Bruce S. McEwen, to commemorate the impact he had on how we understand stress and neuronal plasticity, and the profound influence he exerted on our scientific careers. The ... -
Involvement of the Nucleus Incertus and Relaxin-3/RXFP3 Signaling System in Explicit and Implicit Memory
Gil-Miravet, Isis; Mañas-Ojeda, Aroa; Ros Bernal, Francisco; Castillo-Gómez, Esther; Albert Gasco, Hector; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2021-03-18)Telencephalic cognitive and emotional circuits/functions are strongly modulated by subcortical inputs. The main focus of past research on the nature of this modulation has been on the widespread monoamine projections to ... -
Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice
BUENO FERNANDEZ, CLARA; Perez-Rando, Marta; Alcaide, Julia; Coviello, Simona; Sandi, Carmen; Castillo-Gómez, Esther; Nacher, Juan Elsevier ScienceDirect (2021-04-01)The impact of stressful events is especially important during early life, because certain cortical regions, especially the prefrontal cortex (PFC), are still developing. Consequently, aversive experiences that occur during ... -
MAP/ERK Signaling in Developing Cognitive and Emotional Function and Its Effect on Pathological and Neurodegenerative Processes
Albert Gasco, Hector; Ros, Francisco; Castillo-Gómez, Esther; Olucha-Bordonau, Francisco E MDPI (2020-06-23)The signaling pathway of the microtubule-associated protein kinase or extracellular regulated kinase (MAPK/ERK) is a common mechanism of extracellular information transduction from extracellular stimuli to the intracellular ... -
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex
Navarro Sánchez, Mónica; Gil-Miravet, Isis; Montero Caballero, Daniel; Bathgate, Ross A. D.; Hossain, Mohammed Akhter; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Elsevier (2024-07)The retrosplenial cortex (RSC) plays a central role in processing contextual fear conditioning. In addition to corticocortical and thalamocortical projections, the RSC receives subcortical inputs, including a substantial ... -
Nucleus incertus projections to rat medial septum and entorhinal cortex: rare collateralization and septal-gating of temporal lobe theta rhythm activity
Gil-Miravet, Isis; Nuñez Molina, Angel; Navarro Sánchez, Mónica; Castillo-Gómez, Esther; Ros, Francisco; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Springer (2023)Nucleus incertus (NI) neurons in the pontine tegmentum give rise to ascending forebrain projections and express the neuropeptide relaxin-3 (RLN3) which acts via the relaxin-family peptide 3 receptor (RXFP3). Activity in ... -
Postnatal development of the relaxin-3 innervation of the rat medial septum
ROS, FRANCISCO; Gil-Miravet, Isis; Lucerón Morales, Jorge; Navarro Sánchez, Mónica; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2023)Introduction: The septal area provides a rich innervation to the hippocampus regulating hippocampal excitability to different behavioral states and modulating theta rhythmogenesis. However, little is known about the ... -
Relaxin-3 Innervation From the Nucleus Incertus to the Parahippocampal Cortex of the Rat
García Díaz, Cristina; Gil-Miravet, Isis; Albert Gasco, Hector; Mañas-Ojeda, Aroa; Ros Bernal, Francisco; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2021)Spatial learning and memory processes depend on anatomical and functional interactions between the hippocampus and the entorhinal cortex. A key neurophysiological component of these processes is hippocampal theta rhythm, ... -
Some key parameters in contextual fear conditioning and extinction in adult rats
Navarro Sánchez, Mónica; Gil-Miravet, Isis; Montero Caballero, Daniel; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Elsevier (2024-03-28)Contextual fear conditioning is a behavioral paradigm used to assess hippocampal-dependent memory in experimental animals. Perception of the context depends on activation of a distinct population of neurons in the hippocampus ...