Listar MED_Articles por autoría "0a4faa5a-cf3a-4d44-bcad-edddba4c4bf1"
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Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for b-MSH and desacetyl a-MSH in energy homeostasis
Kirwan, Peter; Kay, Richard G.; Brouwers, Bas; Herranz-Pérez, Vicente; Jura, Magdalena; Larraufie, Pierre; Jerber, Julie; Pembroke, Jason; Bartels, Theresa; White, Anne; Gribble, Fiona M.; Reimann, Frank; Farooqi, I. Sadaf; O’Rahilly, Stephen; Merkle, Florian Elsevier (2018)Objective: The lack of pro-opiomelanocortin (POMC)-derived melanocortin peptides results in hypoadrenalism and severe obesity in both humans and rodents that is treatable with synthetic melanocortins. However, there are ...