• closedAccess   Mucin 1 deficiency mediates corticosteroid insensitivity in asthma 

      MILARA, JAVIER; Morell, Anselm; de Diego, Alfredo; Artigues, Enrique; Morcillo, Esteban; Cortijo, Julio Wiley (2019-01)
      BACKGROUND: The loss of corticosteroid efficacy is an important issue in severe asthma management and may lead to poor asthma control and deterioration of airflow. Recent data indicate that Mucin 1 (MUC1) membrane mucin ...
    • openAccess   Muerte durante una exposición solar prolongada. Golpe de calor versus muerte tóxica 

      De Luis García, María José; Gallart Camahort, Carmen; Molina Aguilar, Pilar; Negre Muñoz, M. Carmen Asociación Nacional de Médicos Forenses (ANMF) (2019)
      Se expone el caso de una mujer de 46 años, de constitución leptosómica, encontrada muerta por su vecino en el jardín de su casa. Había estado tomando el sol durante 8 horas.
    • openAccess   Multidisciplinary expert consensus on secondary fracture prevention in Spain 

      Casado, E.; Blanch, J.; Carbonell, C.; Bastida, J.C.; Pérez-Castrillón, J.L.; Canals, L.; Lizán, Luis Springer (2021-02-27)
      Summary The study aimed to achieve expert consensus to optimize secondary fracture prevention in Spain. Relevant gaps in current patient management were identified. However, some aspects were considered difficult to apply. ...
    • openAccess   Multidisciplinary management of cardiovascular disease in women: Delphi consensus 

      Gámez, José Mª; Pedreira Pérez, Mila; Fernández Olmo, María Rosa; Fasero, Maria; Inaraja, Veronica; Pallarés-Carratalá, Vicente Frontiers (2024)
      Background: Current clinical guidelines on cardiovascular disease (CVD) do not specifically address the female population. The aim of this consensus is to know the opinion of a group of experts on the management of CVD ...
    • openAccess   Multimodular Bio-Inspired Organized Structures Guiding Long-Distance Axonal Regeneration 

      Rodríguez Doblado, Laura; Martínez Ramos, Cristina; Monleón Pradas, Manuel MDPI (2022-09)
      Axonal bundles or axonal tracts have an aligned and unidirectional architecture present in many neural structures with different lengths. When peripheral nerve injury (PNI), spinal cord injury (SCI), traumatic brain injury ...
    • openAccess   Multivariate Analysis of Water Quality Measurements on the Danube River 

      Horvat, Zoltan; Horvat, Mirjana; Pastor, Kristian; Bursic, Vojislava; Puvača, Nikola MDPI (2021-12-17)
      This study investigates the potential of using principal component analysis and other multivariate analysis techniques to evaluate water quality data gathered from natural watercourses. With this goal in mind, a comprehensive ...
    • openAccess   Musical aptitude and silent reading fluency in adult multilingual learners of Spanish: an exploratory study 

      Machancoses, Francisco H.; Legaz, Helena; Buyse, Kris; Fonseca-Mora, M.Carmen Taylor and Francis Group (2022-02-10)
      Skilled adult readers are those who read fluently, but multilingual learners do not always exhibit the same reading proficiency in the different languages they know. Among the variables that influence learners’ silent ...
    • openAccess   Naltrexone Reverses Ethanol-Induced Rat Hippocampal and Serum Oxidative Damage 

      Almansa, Inmaculada; Barcia, Jorge M; López-Pedrajas, Rosa; Muriach, Maria; Miranda, María; Romero, Francisco J. Hindawi Publishing Corporation (2013)
      Naltrexone, an antagonist of 𝜇�-opioid receptors, is clinically used as adjuvant therapy of alcohol dishabituation. The aim of the present work was to test the effect of 1 mg/kg body weight of naltrexone to revert oxidative ...
    • openAccess   Neoadjuvant Chemotherapy plus Interval Cytoreductive Surgery with or without Hyperthermic Intraperitoneal Chemotherapy (NIHIPEC) in the Treatment of Advanced Ovarian Cancer: A Multicentric Propensity Score Study 

      Llueca, Antoni; Ibáñez Gual, Maria Victoria; CASCALES SANCHEZ, PEDRO; Gil-Moreno, Antonio; Bebia, Vicente; Ponce, Jordi; Fernandez, Sergi; Arjona-Sanchez, Alvaro; Muruzabal Torquemada, Juan Carlos; Veiga-Canuto, Nadia; Díaz-Feijoo, Berta; Celada Castro, Cristina; Gilabert-Estellés, Juan; AGHABABYAN, KRISTINA; Lacueva, Francisco Javier; Calero, Alicia; Segura-Sampedro, Juan José; Maiocchi, Karina; Llorca Cardeñosa, Sara; Villarín, Álvaro; CLIMENT MARTÍ, MARIA TERESA; Delgado Barriga, Katty; Serra Rubert, Anna; GOMEZ QUILES, LUIS; Llueca, Maria; Spain GOG and GECOP Working Group MDPI (2023-08-26)
      Simple Summary Advanced ovarian cancer (Stages III-IV) continues to be one of the gynecological tumors with the highest mortality. Standard treatment consists of debulking surgery and subsequent adjuvant chemotherapy. ...
    • openAccess   Neural activity patterns in the chemosensory network encoding vomeronasal and olfactory information in mice 

      Pardo-Bellver, Cecília; Vila Martín, Manuel Esteban; Martínez-Bellver, Sergio; Faus, María Villafranca Frontiers Media (2022)
      Rodents detect chemical information mainly through the olfactory and vomeronasal systems, which play complementary roles to orchestrate appropriate behavioral responses. To characterize the integration of chemosensory ...
    • openAccess   Neural Stem Cells as Potential Glioblastoma Cells of Origin 

      Loras Monfort, Alba; Gonzalez Bonet, Luis Germán; Gutierrez-Arroyo, Julia L.; Martinez-Cadenas, Conrado; Marques-Torrejon, Maria Angeles MDPI (2023)
      Glioblastoma multiforme (GBM) is the most malignant brain tumor in adults and it remains incurable. These tumors are very heterogeneous, resistant to cytotoxic therapies, and they show high rates of invasiveness. Therefore, ...
    • openAccess   Neurogenesis of medium spiny neurons in the nucleus accumbens continues into adulthood and is enhanced by pathological pain 

      García-González, Diego; Dumitru, Ionut; Zuccotti, Annalisa; Yen, Ting-Yu; Herranz-Pérez, Vicente; Tan, Linette Liqi; Angela, Neitz; García-Verdugo, Jose Manuel; Kuner, Rohini; Alfonso, Julieta; Monyer, Hannah Springer Nature (2021)
      In mammals, most adult neural stem cells (NSCs) are located in the ventricular–subventricular zone (V-SVZ) along the wall of the lateral ventricles and they are the source of olfactory bulb interneurons. Adult NSCs exhibit ...
    • openAccess   Neuroinflammation as a possible link between attention-deficit/ hyperactivity disorder (ADHD) and pain 

      Kerekes, Nóra; Sánchez-Pérez, Ana María; Landry, Marc ELSEVIER (2021)
      Attention-deficit/hyperactivity disorder (ADHD) and pathological pain are two complex syndromes of multifactorial origin. Despite their prevalence and broad impacts, these conditions are seldom recognized and managed ...
    • openAccess   Neuronal Bioenergetics and Acute Mitochondrial Dysfunction: A Clue to Understanding the Central Nervous System Side Effects of Efavirenz 

      Funes, Haryes A.; Apostolova, Nadezda; Alegre, Fernando; Blas García, Ana; Álvarez, Ángeles; Martí Cabrera, Miguel; Esplugues Mota, Juan V. Oxford University Press (2014-05)
      Background. Neurological pathogenesis is associated with mitochondrial dysfunction and differences in neuronal/glial handling of oxygen and glucose. The main side effects attributed to efavirenz involve the CNS, but the ...
    • openAccess   New GOLD classification: longitudinal data on group assignment 

      Casanova, Ciro; Marin, Jose M.; Martinez-Gonzalez, Cristina; Lucas-Ramos, Pilar de; Mir-Viladrich, Isabel; Cosio, Borja; Peces-Barba, Germán; Calle-Rubio, Miryam; Solanes-García, Ingrid; Agüero Balbin, Ramón; de Diego, Alfredo; Feu-Collado, Nuria; Alfageme Michavila, Inmaculada; Irigaray, Rosa; Balcells, Eva; Llunell Casanovas, Antònia; Bautista i García, Joan Damià; Marín Royo, Margarita; Soler-Cataluña, Juan J.; Lopez-Campos, Jose Luis; Soriano, Joan B.; Torres, Juan P. de; COPD History Assessment In SpaiN (CHAIN) cohort BioMed Central (2014)
      Rationale: Little is known about the longitudinal changes associated with using the 2013 update of the multidimensional GOLD strategy for chronic obstructive pulmonary disease (COPD). Objective: To determine the COPD ...
    • closedAccess   New insights in primary ciliary dyskinesia 

      Reula, Ana; Moreno-Galdó, Antonio; Romero, Teresa; MILARA, JAVIER; Carda, Carmen; Mata Roig, Manuel; Escribano, Amparo; Dasi, Francisco; Armengot Carceller, Amparo; Lucas, J. S. Taylor & Francis (2017)
      Introduction: Primary ciliary dyskinesia (PCD) is a rare genetic disease with an estimated prevalence of 1:20.000 births. It is characterized by abnormal motility of cilia, leading to impaired mucociliary clearance, and ...
    • openAccess   New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration 

      Kaneko, Naoko; Herranz-Pérez, Vicente; Otsuka, Takanobu; Sano, H.; Ohno, N.; Omata, T.; Nguyen, Huy Bang; Thai, T.Q.; Nambu, A.; Kawaguchi, Yuki; García-Verdugo, Jose Manuel; Sawamoto, Kazunobu American Association for the Advancement of Science (2018)
      After brain injury, neural stem cell–derived neuronal precursors (neuroblasts) in the ventricular-subventricular zone migrate toward the lesion. However, the ability of the mammalian brain to regenerate neuronal ...
    • openAccess   Nigral degeneration correlates with persistent activation of cerebellar Purkinje cells in MPTP-treated monkeys 

      Heman, Paola; Barcia, Carlos; Gómez, Aurora; Ros Gómez, Carmen María; Ros Bernal, Francisco; Yuste Jiménez, José Enrique; De Pablos, Vicente; Fernández Villalba, Emiliano; Toledo-Cárdenas, María Rebeca; Herrero Ezquerro, María Trinidad Universidad de Murcia (2012)
      In the present work we analyze the cerebellum of chronic parkinsonian monkeys in order to clarify whether chronic mesencephalic depletion is associated with long term activation of the cerebellar neurons in chronic ...
    • openAccess   Non-compliance and therapeutic inertia: two unanswered questions in clinical practice 

      Pallarés-Carratalá, Vicente; Pascual Pérez, R. Informa Healthcare (2014)
    • closedAccess   Non-Invasive Mechanical Ventilation Versus Continuous Positive Airway Pressure Relating to Cardiogenic Pulmonary Edema in an Intensive Care Unit 

      Belenguer-Muncharaz, Alberto; Mateu-Campos, Lidon; González-Luís, Rubén; Vidal-Tegedor, Bárbara; Ferrándiz-Sellés, Amparo; Árguedas-Cervera, Joaquín; Altaba-Tena, Susana; Casero-Roig, Patricia; Moreno-Clarí, Ester Elsevier (2017-10)
      Background To compare the application of non-invasive ventilation (NIV) versus continuous positive airway pressure (CPAP) in the treatment of patients with cardiogenic pulmonary edema (CPE) admitted to an intensive care ...