Visualitza Departament: Medicina per autoria "d0ac7496-8253-4e87-a6e4-652bd00c10e4"
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A ciliopathy complex builds distal appendages to initiate ciliogenesis
Kumar, Dhivya; Rains, Addison; Herranz-Pérez, Vicente; Lü, Quanlong; Shi, Xiaoyu; Swaney, Danielle; Stevenson, Erica; Krogan, Nevan; Huang, Bo; Westlake, Christopher; García-Verdugo, Jose Manuel; Yoder, Bradley; Reiter, Jeremy Rockefeller University Press (2021-07-09)Cells inherit two centrioles, the older of which is uniquely capable of generating a cilium. Using proteomics and superresolved imaging, we identify a module that we term DISCO (distal centriole complex). The DISCO components ...