Visualitza Departament: Medicina per autoria "9a4aa3ac-6fb9-44c6-836a-54fe370d3835"
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Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis
Hall, Emma; Kumar, Dhivya; Prosser, Suzanna; Yeyati, Patricia; Herranz-Pérez, Vicente; García-Verdugo, Jose Manuel; rose, lorraine; McKie, Lisa; Dodd, Daniel; Tennant, Peter; Megaw, Roly; Murphy, Laura; Ferreira, Marisa; Grimes, Graeme; Williams, Lucy; Quidwai, Tooba; Pelletier, Laurence; Reiter, Jeremy; Mill, Pleasantine eLife Sciences Publications (2023-02-15)Centrosomes are orbited by centriolar satellites, dynamic multiprotein assemblies nucleated by Pericentriolar Material 1 (PCM1). To study the requirement for centriolar satellites, we generated mice lacking PCM1, a crucial ...