Listar IUPA_Articles por autoría "453755c6-3bc0-4069-9e28-5cf6382d0abf"
Mostrando ítems 81-100 de 111
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Proposal of 5-methoxy-N-methyl-N-isopropyltryptamine consumption biomarkers through identification of in vivo metabolites from mice
Fabregat-Safont, David; Barneo-Muñoz, Manuela; Martinez-Garcia, Fernando; Sancho, Juan V; Hernandez, Felix; Ibáñez, Maria Elsevier (2017-07)New psychoactive substances (NPS) are a new breed of synthetically produced substances designed to mimic the effects of traditional illegal drugs. Synthetic cannabinoids and synthetic cathinones are the two most common ... -
Quadrupole-time-of-flight mass spectrometry screening for synthetic cannabinoids in herbal blends
Ibáñez, Maria; Bijlsma, Lubertus; van Nuijs, Alexander; Sancho, Juan V; Haro, Gonzalo; Covaci, Adrian; Hernandez, Felix John Wiley & Sons (2013-05)‘Legal highs’ are novel substances which are intended to elicit a psychoactive response. They are sold from ‘head shops’, the internet and from street suppliers and may be possessed without legal restriction. Several months ... -
Qualitative screening of 116 veterinary drugs in feed by liquid chromatography-high resolution mass spectrometry. Potential application to quantitative analysis
Boix Sales, Clara; Ibáñez, Maria; Sancho, Juan V; León, Nuria; Yusà, Vicent; Hernandez, Felix Elsevier (2014)Veterinarian and human pharmaceuticals may be intentionally added to animal feed to enhance animal production. Monitoring these substances is necessary for protecting the consumers. In this work, a screening method covering ... -
Qualitative validation of a liquid chromatography-quadrupole-time of flight mass spectrometry screening method for organic pollutants in waters
Díaz San Pedro, Ramón; Ibáñez, Maria; Sancho, Juan V; Hernandez, Felix Elsevier (2013-02)A multiclass wide-scope screening of organic contaminants in natural and waste water has been developed and validated for qualitative purposes, i.e. detection and reliable identification of compounds detected in samples ... -
Quantification, confirmation and screening capability of UHPLC coupled to triple quadrupole and hybrid quadrupole time-of-flight mass spectrometry in pesticide residue analysis
Grimalt Brea, Susana; Sancho, Juan V; Pozo, Óscar J.; Hernandez, Felix John Wiley & Sons (2010-04)The potential of three mass spectrometry (MS) analyzers (triple quadrupole, QqQ; time of flight, TOF; and quadrupole time of flight, QTOF) has been investigated and compared for quantification, confirmation and screening ... -
Rapid wide-scope screening of drugs of abuse, prescription drugs with potential for abuse and their metabolites in influent and effluent urban wastewater by ultrahigh pressure liquid chromatography–quadrupole-time-of-flight-mass spectrometry
Hernandez, Felix; Bijlsma, Lubertus; Sancho, Juan V; Díaz San Pedro, Ramón; Ibáñez, Maria Elsevier (2011-01-17)This work illustrates the potential of hybrid quadrupole-time-of-flight mass spectrometry (QTOF MS) coupled to ultrahigh pressure liquid chromatography (UHPLC) to investigate the presence of drugs of abuse in wastewater. ... -
Reporting the novel synthetic cathinone 5-PPDI through its analytical characterization by mass spectrometry and nuclear magnetic resonance
Fabregat-Safont, David; Carbón, Xoán; Gil Iladanosa, Cristina; Ventura, Mireia; Sancho, Juan V; Hernandez, Felix; Ibáñez, Maria Springer (2018-07)Introduction: User surveys indicate that expectations of higher drug purity are a key reason for cryptomarket use. In 2014–2015, Spain’s NGO Energy Control conducted a 1-year pilot project to ... -
Revealing the differences in collision cross section values of small organic molecules acquired by different instrumental designs and prediction models
Belova, Lidia; Celma, Alberto; Van Haesendonck, Glenn; Lemière, Filip; Sancho, Juan V; Covaci, Adrian; van Nuijs, Alexander; Bijlsma, Lubertus Elsevier (2022-09-09)The number of open access databases containing experimental and predicted collision cross section (CCS) values is rising and leads to their increased use for compound identification. However, the reproducibility of reference ... -
Screening of Pharmaceuticals and Illicit Drugs in Wastewater and Surface Waters of Spain and Italy by High Resolution Mass Spectrometry using UHPLC-QTOF MS and LC-LTQ-Orbitrap MS
Bade, Richard; Rousis, Nikolaos I; Bijlsma, Lubertus; GRACIA LOR, EMMA; Castiglioni, Sara; Sancho, Juan V; Hernandez, Felix Springer (2015)The existence of pharmaceuticals and illicit drugs (PIDs) in environmental waters has led many analytical chemists to develop screening methods for monitoring purposes. Water samples can contain a huge number of possible ... -
Simultaneous determination of acidic, neutral and basic pharmaceuticals in urban wastewater by ultra high-pressure liquid chromatography-tandem mass spectrometry
GRACIA LOR, EMMA; Sancho, Juan V; Hernandez, Felix Elsevier (2010)In this work, an ultra high-pressure liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method has been developed for the simultaneous quantification and confirmation of the 20 most consumed pharmaceuticals in ... -
Simultaneous determination of new psychoactive substances and illicit drugs in sewage: Potential of micro-liquid chromatography tandem mass spectrometry in wastewater-based epidemiology
Celma, Alberto; Sancho, Juan V; Salgueiro-González, Noelia; Castiglioni, Sara; Zuccato, Ettore; Hernandez, Felix; Bijlsma, Lubertus Elsevier (2019-05-30)Wastewater-based epidemiology (WBE) can give valuable light on the extent and actual use of new psychoactive substances (NPS). In this work, a fully validated methodology for the simultaneous determination of illicit drugs ... -
Simultaneous determination of triazines and their main transformation products in surface and urban wastewater by ultra-high-pressure liquid chromatography- tandem mass spectrometry
Benvenuto, Federica; Marín Ramos, José Manuel; Sancho, Juan V; Canobbio, Sergio; Mezzanotte, Valeria; Hernandez, Felix Springer Verlag (2010)This work describes the optimization, validation and application to real samples of an ultra-high-pressure liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method for the quantification and confirmation of 11 ... -
Study of cyanotoxin degradation and evaluation of their transformation products in surface waters by LC-QTOF MS
León, Cristina; Boix Sales, Clara; Beltrán Iturat, Eduardo; Peñuela, Gustavo; Lopez, Francisco; Sancho, Juan V; Hernandez, Felix Elsevier (2019-08)In the present work, the degradation of three cyanotoxins from the hepatotoxins group was investigated under laboratory-controlled experiments in water samples. Surface waters spiked with microcystin-LR (MC-LR), nodularin ... -
Suspect Screening of Large Numbers of Emerging Contaminants in Environmental Waters using Artificial Neural Networks for Chromatographic Retention Time Prediction and High Resolution Mass Spectrometry Data Analysis
Bade, Richard; Bijlsma, Lubertus; Miller, Thomas H.; Barron, León P.; Sancho, Juan V; Hernandez, Felix (2015-12-02)The recent development of broad-scope high resolution mass spectrometry (HRMS) screening methods has resulted in a much improved capability for new compound identification in environmental samples. However, positive ... -
Target and non-target screening strategies for organic contaminants, residues and illicit substances in food , environmental and human biological samples by UHPLC-QTOF-MS
Hernandez, Felix; Díaz San Pedro, Ramón; Sancho, Juan V; Ibáñez, Maria RSC Publishing (2012-01)In this paper, we illustrate the potential of ultra-high performance liquid chromatography (UHPLC) coupled with hybrid quadrupole time-of-flight mass spectrometry (QTOF MS) for large scale screening of organic contaminants ... -
The classification of almonds (Prunus dulcis) by country and variety using UHPLC-HRMS-based untargeted metabolomics
Gil Solsona, Ruben; Boix Sales, Clara; Ibáñez, Maria; Sancho, Juan V Taylor & Francis (2018-01-17)The aim of this study was to use an untargeted UHPLC-HRMS-based metabolomics approach allowing discrimination between almonds based on their origin and variety. Samples were homogenised, extracted with ACN:H2O (80:20) ... -
The key role of mass spectrometry in comprehensive research on new psychoactive substances
Fabregat-Safont, David; Sancho, Juan V; Hernandez, Felix; Ibáñez, Maria John Wiley and Sons (2020-10-29)New psychoactive substances (NPS) are a wide group of compounds that try to mimic the effects produced by the ‘classical’ illicit drugs, including cannabis (synthetic cannabinoids), cocaine and amphetamines (synthetic ... -
The Power of Hyphenated Chromatography/Time-of-Flight Mass Spectrometry in Public Health Laboratories
Hernandez, Felix; Portoles, Tania; Sancho, Juan V; Ibáñez, Maria American Chemical Society (2012)Laboratories devoted to the public health field have to face the analysis of a large number of organic contaminants/residues in many different types of samples. Analytical techniques applied in this field are normally focused ... -
The relevant role of ion mobility separation in LC-HRMS based screening strategies for contaminants of emerging concern in the aquatic environment
Celma, Alberto; Ahrens, Lutz; Gago-Ferrero, Pablo; Hernandez, Felix; Lopez, Francisco; Lundqvist, Johan; Pitarch, Elena; Sancho, Juan V; Wiberg, Karin; Bijlsma, Lubertus Elsevier (2021-05-05)Ion mobility separation (IMS) coupled to high resolution mass spectrometry (IMS-HRMS) is a promising technique for (non-)target/suspect analysis of micropollutants in complex matrices. IMS separates ionized compounds based ... -
The role of analytical chemistry in exposure science: Focus on the aquatic environment
Hernandez, Felix; Bakker, Joost; Bijlsma, Lubertus; De Boer, Jacob H.; Botero-Coy, Ana Maria; Bruinen de Bruin, Yuri; Fischer, Stellan Taylor; Hollender, Juliane; Kasprzyk-Hordern, Barbara; Lamoree, Marja; López, F. J.; Laak, Thomas Lter; Van Leerdam, Jan A.; Sancho, Juan V; Schymanski, Emma; De Voogt, Pim W.P.; Hogendoorn, Elbert Alex Elsevier (2019-05)Exposure science, in its broadest sense, studies the interactions between stressors (chemical, biological, and physical agents) and receptors (e.g. humans and other living organisms, and non-living items like buildings), ...