Listar IUPA_Articles por autoría "453755c6-3bc0-4069-9e28-5cf6382d0abf"
Mostrando ítems 101-111 de 111
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Told through the wine: A liquid chromatography–mass spectrometry interplatform comparison reveals the influence of the global approach on the final annotated metabolites in non-targeted metabolomics
Díaz San Pedro, Ramón; Gallart-Ayala, Héctor; Sancho, Juan V; Nuñez, Óscar; Zamora, T.; Martins, Claudia P.B.; Hernandez, Felix; Hernández-Cassou, Santiago; Saurina, Javier; Checa, Antonio Elsevier (2016)This work focuses on the influence of the selected LC-HRMS platform on the final annotated compounds in non-targeted metabolomics. Two platforms that differed in columns, mobile phases, gradients, chromatographs, mass ... -
Triacylglycerol Analysis in Human Milk and Other Mammalian Species: Small-Scale Sample Preparation, Characterization, and Statistical Classification Using HPLC-ELSD Profiles
Ten Doménech, Isabel; Beltrán Iturat, Eduardo; Herrero Martínez, José Manuel; Sancho, Juan V; Simó-Alfonso, Ernesto Francisco American Chemical Society (2015-06)In this work, a method for the separation of triacylglycerols (TAGs) present in human milk and from other mammalian species by reversed-phase high-performance liquid chromatography using a core–shell particle packed column ... -
UHPLC–MS/MS highly sensitive determination of aflatoxins, the aflatoxin metabolite M1 and ochratoxin A in baby food and milk
Beltrán Iturat, Eduardo; Ibáñez, Maria; Sancho, Juan V; Cortés, Miguel Ángel; Yusà, Vicent; Hernandez, Felix Elsevier (2011)In this work, a method has been developed for the ultrasensitive and selective determination of various regulated mycotoxins (aflatoxins G1, G2, B1, B2, M1, and ochratoxin A) in baby food commodities and milk, using ultra ... -
Ultra-Performance Liquid Chromatography-Ion Mobility Separation-Quadruple Time-of-Flight MS (UHPLC-IMS-QTOF MS) Metabolomics for Short-Term Biomarker Discovery of Orange Intake: A Randomized, Controlled Crossover Study
Lacalle-Bergeron, Leticia; Portoles, Tania; López, Francisco J.; Sancho, Juan V; CAROLINA, ORTEGA-AZORÍN; Asensio, Eva Maria; Coltell, Oscar; Corella, Dolores MDPI (2020)A major problem with dietary assessments is their subjective nature. Untargeted metabolomics and new technologies can shed light on this issue and provide a more complete picture of dietary intake by measuring the profile ... -
Understanding the pharmacokinetics of synthetic cathinones: Evaluation of the blood–brain barrier permeability of 13 related compounds in rats
Fabregat-Safont, David; Barneo-Muñoz, Manuela; Carbón, Xoán; Hernandez, Felix; Martinez-Garcia, Fernando; Ventura, Mireia; Stove, Christophe P.; Sancho, Juan V; Ibáñez, Maria Wiley (2020)Synthetic cathinones are the second most commonly seized new psychoactive substance family in Europe. These compounds have been related to several intoxication cases, including fatalities. Although the pharmacological ... -
Untargeted metabolomics based on ultra-high-performance liquid chromatography-ion mobility-quadrupole time-of-flight mass spectrometry for biomarker discovery of orange intake in a cross-over trial
Portoles, Tania; Coltell, Oscar; Lacalle-Bergeron, Leticia; Sancho, Juan V; Lopez, Francisco; CAROLINA, ORTEGA-AZORÍN; Asensio, Eva Maria; Corella, Dolores Gordon Research Conferences (2019-02-03)Diet is one of the most important lifestyle factors associated with health status. Currently, one of the main limitations of nutritional epidemiology and nutritional genomics is the difficulty in the measurements of dietary ... -
Untargeted Metabolomics in Doping Control: Detection of New Markers of Testosterone Misuse by Ultrahigh Performance Liquid Chromatography Coupled to High-Resolution Mass Spectrometry
Raro Macián, Montserrat; Ibáñez, Maria; Gil Solsona, Ruben; Fabregat, Andreu; Tudela, Eva; Deventer, Koen; Ventura, Rosa; Segura, Jordi; Marcos, Josep; Kotronoulas, Aristotelis; Joglar, Jesús; Farré, Magi; Yang, Sheng; Xing, Yanyi; Van Eenoo, Peter; Pitarch, Elena; Hernandez, Felix; Sancho, Juan V; Pozo, Óscar J. American Chemical Society (2015)The use of untargeted metabolomics for the discovery of markers is a promising and virtually unexplored tool in the doping control field. Hybrid quadrupole time-of- flight (QTOF) and hybrid quadrupole Orbitrap (Q ... -
Use of electron ionization and atmospheric pressure chemical ionization in gas chromatography coupled to time-of-flight mass spectrometry for screening and identification of organic pollutants in waters
Portoles, Tania; Mol, Johannes G. J.; Sancho, Juan V; Hernandez, Felix Elsevier (2014-04)A new approach has been developed for multiclass screening of organic contaminants in water based on the use of gas chromatography coupled to hybrid quadrupole high-resolution time-of-flight mass spectrometry with atmospheric ... -
Use of ion mobility-high resolution mass spectrometry in metabolomics studies to provide near MS/MS quality data in a single injection
Gil Solsona, Ruben; Sancho, Juan V; Gassner, Anne-Laure; Céline, Weyermann; Hernández Domínguez, Félix; Delémont, Olivier; Bijlsma, Lubertus John Wiley and Sons (2021-03-10)The use of ion mobility separations (IMSs) in metabolomics approaches has started to be deeply explored in the last years. In this work, the use of liquid chromatography (LC) coupled to IMS-quadrupole time-of-flight mass ... -
Validation of a qualitative screening method for pesticides in fruits and vegetables by gas chromatography quadrupole-time of flight mass spectrometry with atmospheric pressure chemical ionization
Portoles, Tania; Mol, Johannes G. J.; Sancho, Juan V; Lopez, Francisco; Hernandez, Felix Elsevier (2014-08-01)A wide-scope screening method was developed for the detection of pesticides in fruit and vegetables. The method was based on gas chromatography coupled to a hybrid quadrupole time-of-flight mass spectrometer with an ... -
What about the herb? A new metabolomics approach for synthetic cannabinoid drug testing
Bijlsma, Lubertus; Gil Solsona, Ruben; Hernandez, Felix; Sancho, Juan V Springer Verlag (2018-08)Synthetic cannabinoids (SCs) are consumed as legal alternative to cannabis and often allow passing drug-screening tests. Their rapid transience on the drug scene, combined with their mostly unknown metabolic profiles, ...