Listar IUPA_Articles por autoría "12230843-9d8f-4b45-a692-d9e50c3c9630"
Mostrando ítems 1-11 de 11
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Analytical strategy to investigate 3,4-methylenedioxypyrovalerone (MDPV) metabolites in consumers’ urine by high-resolution mass spectrometry
Ibáñez, Maria; Pozo, Óscar J.; Sancho, Juan V; Orengo, Teresa; Haro, Gonzalo; Hernandez, Felix Springer (2016-01)The potential of high-resolution mass spectrometry (HRMS) for the investigation of human in vivo metabolism of 3,4-methylenedioxypyrovalerone (MDPV) using urine collected from a consumer (this is, in non-controlled ... -
Determination of selected endogenous anabolic androgenic steroids and ratios in urine by ultra high performance liquid chromatography tandem mass spectrometry and isotope pattern deconvolution
Pitarch-Motellón, Jorge; Sancho, Juan V; Ibáñez, Maria; Pozo, Óscar J.; Roig-Navarro, Antoni F. Elsevier (2017-09)An isotope dilution mass spectrometry (IDMS) method for the determination of selected endogenous anabolic androgenic steroids (EAAS) in urine by UHPLC–MS/MS has been developed using the isotope pattern deconvolution (IPD) ... -
Evaluation of uncertainty sources in the determination of testosterone in urine by calibration-based and isotope dilution quantification using ultra high performance liquid chromatography tandem mass spectrometry
Pitarch-Motellón, Jorge; Roig-Navarro, Antoni F.; Sancho, Juan V; Ibáñez, Maria; Fabregat-Cabello, Neus; Pozo, Óscar J.; Ventura, Rosa; García Alonso, J. Ignacio; Rodríguez González, Pablo; González Gago, Adriana; Ereño Artabe, Amaia; Van Eenoo, Peter; Deventer, Koen; Dehnes, Yvette; Rzeppa, Sebastian Elsevier (2017-06)Three quantification methodologies, namely calibration with internal standard (Cal-IS, non-weighted), weighted calibration with internal standard (wCal-IS) and isotope pattern deconvolution (IPD) have been used for the ... -
Isotope Dilution LC-ESI-MS/MS and low resolution Selected Reaction Monitoring as a tool for the accurate quantification of urinary testosterone
Ereño Artabe, Amaia; Gonzalez-Gago, Adriana; Suarez Fernández, Amanda; Pitarch-Motellón, Jorge; Roig-Navarro, Antoni F.; Pozo, Óscar J.; Rodríguez González, Pablo; García Alonso, J. Ignacio Elsevier (2018-09)A new analytical method for the quantification of testosterone in human urine samples by isotope dilution mass spectrometry is proposed. A standard solution of 13C2-testosterone is added to the samples at the beginning of ... -
Mass spectrometric behavior of anabolic androgenic steroids using gas chromatography coupled to atmospheric pressure chemical ionization source. Part I: Ionization
Raro Macián, Montserrat; Portoles, Tania; Sancho, Juan V; Pitarch, Elena; Hernandez, Felix; Marcos, Josep; Ventura, Rosa; Gómez, C.; Segura, Jordi; Pozo, Óscar J. John Wiley & Sons (2014-05)The detection of anabolic androgenic steroids (AAS) is one of the most important topics in doping control analysis. Gas chromatography coupled to (tandem) mass spectrometry (GC–MS(/MS)) with electron ionization and liquid ... -
Mass spectrometric characterisation of acondensation product betweenporphobilinogen and indolyl-3-acryloylglycinein urine of patients with acuteintermittent porphyria
Ibáñez, Maria; Marcos, Josep; Ventura, Rosa; Segura, Jordi; Pozo, Óscar J.; To-Figueras, Jordi Wiley (2015-07)We document the presence of a previously unknown species in the urine of patients with acute intermittent porphyria (AIP). Thecompound was fully characterised by liquid chromatography tandem mass spectrometry. Interpretation ... -
Mass Spectrometric Evaluation of Mephedrone In Vivo Human Metabolism: Identification of Phase I and Phase II Metabolites, Including a Novel Succinyl Conjugate
Pozo, Óscar J.; Ibáñez, Maria; Sancho, Juan V; Lahoz-Beneytez, Julio; Farré, Magi; Papaseit, Esther; De la Torre, Rafael; Hernandez, Felix American Society for Pharmacology and Experimental Therapeutics (ASPET) (2015-02)In recent years, many new designer drugs have emerged, including the group of cathinone derivatives. One frequently occurring drug is mephedrone; although mephedrone was originally considered as a “legal high” product, it ... -
Metabolomic approaches for orange origin discrimination by ultra-high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry
Díaz, Ramon; Pozo, Óscar J.; Sancho, Juan V; Hernandez, Felix Elsevier (2014)In this work, hybrid quadrupole time-of-flight mass spectrometer (QTOF MS) coupled to ultra high performance liquid chromatography (UHPLC) has been used for biomarkers identification for correct authentication of Valencia ... -
Potential of atmospheric pressure chemical ionization source in gas chromatography tandem mass spectrometry for the screening of urinary exogenous androgenic anabolic steroids
Raro Macián, Montserrat; Portoles, Tania; Pitarch, Elena; Sancho, Juan V; Hernandez, Felix; Garrostas, L.; Marcos, Josep; Ventura, Rosa; Segura, Jordi; Pozo, Óscar J. Elsevier (2016-02-04)The atmospheric pressure chemical ionization (APCI) source for gas chromatography-mass spectrometry analysis has been evaluated for the screening of 16 exogenous androgenic anabolic steroids (AAS) in urine. The sample ... -
Quantification, confirmation and screening capability of UHPLC coupled to triple quadrupole and hybrid quadrupole time-of-flight mass spectrometry in pesticide residue analysis
Grimalt Brea, Susana; Sancho, Juan V; Pozo, Óscar J.; Hernandez, Felix John Wiley & Sons (2010-04)The potential of three mass spectrometry (MS) analyzers (triple quadrupole, QqQ; time of flight, TOF; and quadrupole time of flight, QTOF) has been investigated and compared for quantification, confirmation and screening ... -
Untargeted Metabolomics in Doping Control: Detection of New Markers of Testosterone Misuse by Ultrahigh Performance Liquid Chromatography Coupled to High-Resolution Mass Spectrometry
Raro Macián, Montserrat; Ibáñez, Maria; Gil Solsona, Ruben; Fabregat, Andreu; Tudela, Eva; Deventer, Koen; Ventura, Rosa; Segura, Jordi; Marcos, Josep; Kotronoulas, Aristotelis; Joglar, Jesús; Farré, Magi; Yang, Sheng; Xing, Yanyi; Van Eenoo, Peter; Pitarch, Elena; Hernandez, Felix; Sancho, Juan V; Pozo, Óscar J. American Chemical Society (2015)The use of untargeted metabolomics for the discovery of markers is a promising and virtually unexplored tool in the doping control field. Hybrid quadrupole time-of- flight (QTOF) and hybrid quadrupole Orbitrap (Q ...