Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines D and M
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Other documents of the author: Ribés Vidal, Celia; Falomir, Eva; Murga, Juan; Carda, Miguel; Marco, J. Alberto
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Title
Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines D and MDate
2011-06-03Publisher
Royal Society of ChemistryISSN
1477-0520Bibliographic citation
RIBES, Celia, et al. Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines D and M. Organic & biomolecular chemistry, 2009, vol. 7, no 7, p. 1355-1360.Type
info:eu-repo/semantics/articleSubject
Abstract
The first syntheses of the polyhydroxylated alkaloids (iminosugars) broussonetines D and M
glycosidase inhibitors of the pyrrolidine class, have been performed in a convergent, stereocontrolled
way from D-serine as ... [+]
The first syntheses of the polyhydroxylated alkaloids (iminosugars) broussonetines D and M
glycosidase inhibitors of the pyrrolidine class, have been performed in a convergent, stereocontrolled
way from D-serine as the chiral starting material. A cross metathesis step was one key feature of the
synthesis. The versatility of the synthetic concept chosen permits the access to many members of this
compound family, both natural ones and analogues thereof [-]
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Organic & biomolecular chemistry, 2009, v. 7Rights
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