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In-hospital versus after-discharge complete revascularization in patients with ST segment elevation myocardial infarction and multivessel disease. REVIVA-ST trial
dc.contributor.author | Rumiz, Eva | |
dc.contributor.author | Valero, Ernesto | |
dc.contributor.author | Fernandez, Carmen | |
dc.contributor.author | Vilar, Juan Vicente | |
dc.contributor.author | Pellicer, Mauricio | |
dc.contributor.author | Cubillos, Andres | |
dc.contributor.author | Berenguer, Alberto | |
dc.contributor.author | Facila Rubio, Lorenzo | |
dc.contributor.author | Vaño, Joan | |
dc.contributor.author | Núñez, Julio | |
dc.date.accessioned | 2024-08-01T09:47:17Z | |
dc.date.available | 2024-08-01T09:47:17Z | |
dc.date.issued | 2024-05-14 | |
dc.identifier.citation | Rumiz E, Valero E, Fernandez C, Vilar JV, Pellicer M, Cubillos A, et al. (2024) In-hospital versus after-discharge complete revascularization in patients with ST segment elevation myocardial infarction and multivessel disease. REVIVA-ST trial. PLoS ONE 19(5): e0303284. | ca_CA |
dc.identifier.issn | 1932-6203 | |
dc.identifier.uri | http://hdl.handle.net/10234/208445 | |
dc.description.abstract | -Introduction : Complete revascularization (CR) in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD), is associated with a reduction in major adverse cardiovascular events (MACE). However, there is uncertainty about whether nonculprit-lesion revascularization should be performed, during index hospitalization or delayed, especially regarding health care resources utilization. In this study, we aimed to evaluate the impact of in-hospital nonculprit-lesion revascularization vs. delayed (after discharge) revascularization on the length of index hospitalization. -Methods : In this single-center study, we randomly assigned patients with STEMI and MVD who underwent successful culprit-lesion PCI to a strategy of either CR during in-hospital admission or a delayed CR after discharge. The first primary endpoint was the length of hospital stay. The second endpoint was the composite of cardiovascular death, myocardial infarction or ischemia-driven revascularization at 12 months (MACE). -Results : From January 2018 to December 2022, we enrolled 258 patients (131 allocated to CR during in-hospital admission and 127 to an after-discharge CR). We found a significant reduction in the length of hospital stay in those assigned to after-discharge CR strategy [4 days (3–5) versus 7 days (5–9); p = 0.001]. At 12-month of follow-up, no differences were found in the occurrence of MACE, 7 (5.34%) patients in in-hospital CR and 4 (3.15%) in after-discharge CR strategy; (hazard ratio, 0.59; 95% confidence interval, 0.17 to 2.02; p = 0.397). -Conclusions : In STEMI patients with MVD, an after-discharge CR strategy reduces the length of index hospitalization without an increased risk of MACE after 12 months of follow-up. | ca_CA |
dc.format.extent | 12 p. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Public Library of Science | ca_CA |
dc.relation.isPartOf | PLoS ONE 19(5) (2024) | ca_CA |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | ca_CA |
dc.subject | revascularization | ca_CA |
dc.subject | hospitals | ca_CA |
dc.subject | lesions | ca_CA |
dc.subject | coronary revascularization | ca_CA |
dc.subject | myocardial infarction | ca_CA |
dc.subject | coronary heart disease | ca_CA |
dc.title | In-hospital versus after-discharge complete revascularization in patients with ST segment elevation myocardial infarction and multivessel disease. REVIVA-ST trial | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | https://doi.org/10.1371/journal.pone.0303284 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |
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