Liquid chromatography, a valuable tool in the determination of antibiotics in biological, food and environmental samples
Visualitza/
Impacte
Scholar |
Altres documents de l'autoria: Vives-Peris, Vicente; Peris García, Ester; Albiol Chiva, Jaume; Durgbanshi, Abhilasha; Ochoa-Aranda, Enrique; Carda-Broch, Samuel; Bose, Devasish; Esteve-Romero, Josep
Metadades
Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7013
comunitat-uji-handle3:10234/8638
comunitat-uji-handle4:
INVESTIGACIONMetadades
Títol
Liquid chromatography, a valuable tool in the determination of antibiotics in biological, food and environmental samplesAutoria
Data de publicació
2022-06-05Editor
Elsevier B.V.ISSN
0026-265XCita bibliogràfica
Peris-Vicente, J., Peris-García, E., Albiol-Chiva, J., Durgbanshi, A., Ochoa-Aranda, E., Carda-Broch, S., Bose, D. & Esteve-Romero, J. (2022). Liquid chromatography, a valuable tool in the determination of antibiotics in biological, food and environmental samples. Microchemical Journal, 107309.Tipus de document
info:eu-repo/semantics/articleVersió
info:eu-repo/semantics/publishedVersionParaules clau / Matèries
Resum
This review is the result of a survey across the bibliography about the determination of several antibiotics in
biological, food and environmental samples by liquid chromatography. Their determination in those samples ... [+]
This review is the result of a survey across the bibliography about the determination of several antibiotics in
biological, food and environmental samples by liquid chromatography. Their determination in those samples is
usually made in clinical monitoring, food safety and environmental studies. A brief description of the pharmacological activity is provided, to complement the relevance of the topic bioanalytical method. Exposure to
antimicrobial agents, which can be evaluated by the analysis of biological fluids, comes mainly from their
extensive use as veterinary agents in industrial animal farming, via food chain and residual water poured to the
environment. Common columns and mobile phases are C18 ones and mixtures of aqueous buffers, acetonitrile
and methanol, respectively. Retention times of these analyses are 20–30 min with column temperatures ranging
from 15 to 45 ◦C and injection volumes of 10–20 µL. Detection is mainly performed by UV–Visible absorbance
and MS/MS detection in positive mode, excluding glycopeptides where fluorescence was used. These procedures
exhibit adequate analytical performances: good selectivity, precision, linearity range, ruggedness and sensitivity,
though variable trueness. The future trend in the management and control of antibiotics in the here studied
samples should be the development of automatized on-line detection protocols (sample processing coupled to
chromatographic separation) for currently studied antibiotics and new methods for unknown metabolites and the
transformation products. [-]
Publicat a
Microchemical Journal, Vol. 177 (June 2022)Entitat finançadora
Ministerio de Ciencia e Innovación (MCIN) | Department of Science and Technology; Ministry of Science and Technology; Government of India | Universitat de València
Codi del projecte o subvenció
PID2019-106708 GB-I00 | /AEI/10.13039/ 501100011033
Drets d'accés
© 2022 The Author(s).
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Apareix a les col.leccions
- QFA_Articles [826]