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Thyrotoxicosis following SARS-COV-2 vaccination: a case series and discussion
dc.contributor.author | Pla Peris, Begoña | |
dc.contributor.author | Merchante Alfaro, A. Á. | |
dc.contributor.author | Maravall Royo, F. J. | |
dc.contributor.author | Abellán-Galiana, Pablo | |
dc.contributor.author | Pérez Naranjo, S. | |
dc.contributor.author | González Boillos, Margarita | |
dc.date.accessioned | 2022-10-03T11:43:15Z | |
dc.date.available | 2022-10-03T11:43:15Z | |
dc.date.issued | 2022-01-11 | |
dc.identifier.citation | Pla Peris, B., Merchante Alfaro, A.Á., Maravall Royo, F.J. et al. Thyrotoxicosis following SARS-COV-2 vaccination: a case series and discussion. J Endocrinol Invest 45, 1071–1077 (2022). https://doi.org/10.1007/s40618-022-01739-0 | ca_CA |
dc.identifier.issn | 0391-4097 | |
dc.identifier.issn | 1720-8386 | |
dc.identifier.uri | http://hdl.handle.net/10234/200098 | |
dc.description.abstract | Aim To describe a case series of thyrotoxicosis likely triggered by SARS-CoV-2 vaccination and to warn physicians about this potential correlation. To report clinical, laboratory and imaging fndings and provide further information that goes in line with the underlying mechanisms. Methods Single-center case series based on all the information collected in the hospital medical records, as well as the temporal sequence between the onset of symptoms and COVID-19 vaccination. Results We report 8 cases with thyrotoxicosis after SARS-CoV-2 vaccination. 4 cases of Graves’ disease (GD), 2 cases of subacute painful thyroiditis (SAT), 1 case of concurrent GD and SAT and 1 case of atypical subacute thyroiditis. Five patients received BNT162b2 mRNA vaccine, 3 patients 1273 mRNA vaccine. The onset of symptoms following vaccination ranged from 10 to 14 days in six of eight patients and from 7 to 8 weeks in two patients. Conclusions Several hypotheses have been proposed to explain the potential correlation between SARS-CoV-2 vaccination and thyrotoxicosis, including immune system hyper-stimulation, molecular mimicry and Autoimmune/Autoinfammatory Syndrome Induced by Adjuvants (ASIA). We should pay greater attention to thyroid disorders in patients receiving vaccine against SARS-CoV-2. | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Springer | ca_CA |
dc.relation.isPartOf | Journal of Endocrinological Investigation, volume 45, pages1071–1077 (2022) | ca_CA |
dc.rights | Copyright © 2022, Italian Society of Endocrinology (SIE) | ca_CA |
dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | ca_CA |
dc.subject | SARS-CoV-2 vaccination | ca_CA |
dc.subject | thyrotoxicosis | ca_CA |
dc.subject | subacute painful thyroiditis | ca_CA |
dc.subject | graves’ disease | ca_CA |
dc.subject | autoimmune syndrome | ca_CA |
dc.subject | adjuvants | ca_CA |
dc.title | Thyrotoxicosis following SARS-COV-2 vaccination: a case series and discussion | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | https://doi.org/10.1007/s40618-022-01739-0 | |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |
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