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New psychoactive substances in several European populations assessed by wastewater-based epidemiology
dc.contributor.author | Castiglioni, Sara | |
dc.contributor.author | Salgueiro-González, Noelia | |
dc.contributor.author | Bijlsma, Lubertus | |
dc.contributor.author | Celma, Alberto | |
dc.contributor.author | GRACIA LOR, EMMA | |
dc.contributor.author | Beldean-Galea, Mihail Simion | |
dc.contributor.author | Mackuľak, Tomáš | |
dc.contributor.author | Emke, Erik | |
dc.contributor.author | Heath, Ester | |
dc.contributor.author | Kasprzyk-Hordern, Barbara | |
dc.contributor.author | Kovacevic, Andjelka | |
dc.contributor.author | Poretti, Francesco | |
dc.contributor.author | Rangelov, Jeliaz | |
dc.contributor.author | Santos, Miguel M. | |
dc.contributor.author | Sremački, Maja | |
dc.contributor.author | Hernandez, Felix | |
dc.contributor.author | Zuccato, Ettore | |
dc.date.accessioned | 2021-04-15T10:44:01Z | |
dc.date.available | 2021-04-15T10:44:01Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Volume 195, 1 May 2021 | ca_CA |
dc.identifier.issn | 0043-1354 | |
dc.identifier.uri | http://hdl.handle.net/10234/192857 | |
dc.description.abstract | Wastewater-based epidemiology (WBE) can be a useful tool to face some of the existing challenges in monitoring the use of new psychoactive substances (NPS), as it can provide objective and updated infor- mation. This Europe-wide study aimed to verify the suitability of WBE for investigating the use of NPS. Selected NPS were monitored in urban wastewater by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS). The main classical illicit drugs were monitored in the same samples to compare their levels with those of NPS. Raw composite wastewater samples were collected in 2016 and 2017 in 14 European countries (22 cities) following best practice sampling protocols. Methcathinone was most frequent ( > 65% of the cities), followed by mephedrone ( > 25% of the cities), and only mephedrone, methcathinone and methylone were found in both years. This study depicts the use of NPS in Europe, confirming that it is much lower than the use of classical drugs. WBE proved able to assess the qualita- tive and quantitative spatial and temporal profiles of NPS use. The results show the changeable nature of the NPS market and the importance of large WBE monitoring campaigns for selected priority NPS. WBE is valuable for complementing epidemiological studies to follow rapidly changing profiles of use of drugs. | ca_CA |
dc.format.extent | 10 p. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Elsevier | ca_CA |
dc.relation | Proyecto de tesis doctoral de Alberto Celma Tirado + estada: investigación sobre el uso de nuevas sustancias psicoactivas a través del análisis de los productos consumidos, de la orina de potenciales consumidores y de aguas residuales | ca_CA |
dc.relation | Investigación sobre el uso de nuevas sustancias psicoactivas a través del análisis de los productos consumidos, de la orina de potenciales consumidores y de aguas residuales urbanas | ca_CA |
dc.relation | Química analítica y salud pública. Aportaciones de la espectometría de masas de alta resolución. | ca_CA |
dc.relation | Identification and assessment of new psychoactive substances: a european network | ca_CA |
dc.rights.uri | http://rightsstatements.org/vocab/CNE/1.0/ | * |
dc.subject | Urban wastewater | ca_CA |
dc.subject | New psychoactive substances | ca_CA |
dc.subject | Monitoring | ca_CA |
dc.subject | Europe | ca_CA |
dc.subject | Spatial and temporal trends | ca_CA |
dc.subject | Use profiles | ca_CA |
dc.title | New psychoactive substances in several European populations assessed by wastewater-based epidemiology | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | 10.1016/j.watres.2021.116983 | |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | ca_CA |
dc.relation.publisherVersion | https://www.sciencedirect.com/science/article/pii/S0043135421001810?via%3Dihub | ca_CA |
dc.relation.publisherVersion | https://www.sciencedirect.com/science/article/pii/S0043135421001810?via%3Dihub | ca_CA |
dc.relation.ispartof | https://www.sciencedirect.com/science/article/pii/S0043135421001810?via%3Dihub | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |
oaire.awardNumber | BES-2016-076914 | ca_CA |
oaire.awardNumber | CTQ2015-65603-P | ca_CA |
oaire.awardNumber | PROMETEO/2019/040 | ca_CA |
oaire.awardNumber | 2014/JDRU/AG/DRUG/7086 | ca_CA |
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