First nation-wide estimation of tobacco consumption in Spain using wastewater-based epidemiology
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Otros documentos de la autoría: Montes, Rosa; Rodil, Rosario; Rico, Andreu; Cela, Rafael; González-Mariño, Iria; Hernandez, Felix; Bijlsma, Lubertus; Celma, Alberto; Picó Gracia, Yolanda; Andreu, Vicente; López de Alda, Miren; López-García, Ester; Postigo, Cristina; Pocurull, Eva; Marcé, Rosa María; Rosende, María; Olivares, Maitane; Valcárcel, Yolanda; Quintana, José Benito
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INVESTIGACIONMetadatos
Título
First nation-wide estimation of tobacco consumption in Spain using wastewater-based epidemiologyAutoría
Fecha de publicación
2020-11-01Editor
ElsevierISSN
0048-9697; 1879-1026Cita bibliográfica
MONTES, Rosa, et al. First nation-wide estimation of tobacco consumption in Spain using wastewater-based epidemiology. Science of The Total Environment, 2020, vol. 741, p. 140384Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://www.sciencedirect.com/science/article/pii/S0048969720339061#!Versión
info:eu-repo/semantics/acceptedVersionPalabras clave / Materias
Resumen
Wastewater-based epidemiology (WBE) has become a very useful tool to monitor a
population’s drug consumption or exposure to environmental and food contaminants. In this
work, WBE has been applied to estimate tobacco ... [+]
Wastewater-based epidemiology (WBE) has become a very useful tool to monitor a
population’s drug consumption or exposure to environmental and food contaminants. In this
work, WBE has been applied to estimate tobacco consumption in seven Spanish regions. To
this end, 24 h composite wastewater samples were taken daily for one week in 17 wastewater
treatment plants, covering altogether a population of ca. 6 million inhabitants. The samples
were treated by enzymatic deconjugation and the wastewater content of two human-specific
nicotine metabolites (namely, cotinine and trans-3′-hydroxycotinine) was measured to
estimate the daily consumption of nicotine. The population-weighted average nicotine
consumption in the seven analyzed regions was 2.2 g/(day∙1000 inh.), without any daily
pattern. This average estimated nicotine consumption value agreed with the value derived
from official tobacco sales data. Differences in consumption among the seven studied regions
were found, being Galicia, the region with the lowest rate, and the Basque Country and
Catalonia those with the highest rates. However, no conclusive correlation was found
between those values and the prevalence data taken from two different national surveys, nor
sociodemographic and health data. This study demonstrates that this tool can complement
other indicators in order to accurately assess tobacco consumption rates at regional and
national levels and provides the most extensive application of the approach in the Spanish
territory. [-]
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Science of The Total Environment, 2020, vol. 741, p. 140384Proyecto de investigación
This study was supported by MINECO/AEI projects (CTM2016-81935-REDT, CTM2017-84763-C3-2-R, CTM2017-84763-C3-1-R, CTM2017-84763-C3-3-R), MICINN project (CEX2018-000794-S), Galician Council of Culture, Education and Universities (ED481D 2017/003 and ED431C2017/36), cofunded by FEDER/ERDF.Derechos de acceso
info:eu-repo/semantics/openAccess
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