Mostrar el registro sencillo del ítem
Right Ventricular Dysfunction Staging System for Mortality Risk Stratifiction in Heart Failure with Preserved Ejection Fraction
dc.contributor.author | Santas, Enrique | |
dc.contributor.author | De la Espriella, Rafael | |
dc.contributor.author | Chorro, Francisco J. | |
dc.contributor.author | Palau, Patricia | |
dc.contributor.author | Miñana, Gema | |
dc.contributor.author | Heredia, Raquel | |
dc.contributor.author | Amiguet Comins, Martina | |
dc.contributor.author | Merenciano Gonzalez, Hector | |
dc.contributor.author | Sanchis, Juan | |
dc.contributor.author | Lupón, Josep | |
dc.contributor.author | Bayes-Genis, Antoni | |
dc.contributor.author | Núñez, Julio | |
dc.date.accessioned | 2020-07-10T08:08:23Z | |
dc.date.available | 2020-07-10T08:08:23Z | |
dc.date.issued | 2020-03-18 | |
dc.identifier.citation | Santas E, De la Espriella R, Chorro FJ, et al. Right Ventricular Dysfunction Staging System for Mortality Risk Stratification in Heart Failure With Preserved Ejection Fraction. J Clin Med. 2020;9(3):831. Published 2020 Mar 18. doi:10.3390/jcm9030831 | ca_CA |
dc.identifier.uri | http://hdl.handle.net/10234/189074 | |
dc.description.abstract | Right ventricular dysfunction (RVD) parameters are increasingly important features in heart failure with preserved ejection fraction (HFpEF). We sought to evaluate the prognostic impact of a progressive RVD staging system by combining the tricuspid annular plane systolic excursion (TAPSE) to pulmonary artery systolic pressure (TAPSE/PASP) ratio with functional tricuspid regurgitation (TR) severity. We prospectively included 1355 consecutive HFpEF patients discharged for acute heart failure (HF). Of them, in 471 (34.7%) patients, PASP could not be accurately measured, leaving the final sample size to be 884 patients. Patients were categorized as Stage 1: TAPSE/PASP ≥ 0.36 without significant TR; stage 2: TAPSE/PASP ≥ 0.36 with significant TR; stage 3: TAPSE/PASP < 0.36 without significant TR; and stage 4: TAPSE/PASP < 0.36 with significant TR. By the 1 year follow-up, 207 (23.4%) patients had died. We found a significant and graded association between RVD stages and mortality rates (15.8%, 25%, 31.2%, and 45.4% from stage 1 to stage 4, respectively; log-rank test, p < 0.001). After multivariable adjustment, and compared to stage 1, stages 3 and 4 were independently associated with mortality risk (HR: 1.8219; 95% CI 1.308-2.538; p < 0.001 and HR = 2.2632; 95% CI 1.540-3.325; p < 0.001, respectively). A RVD staging system, integrating TAPSE/PASP and TR, provides a comprehensive and widely available tool for risk stratification in HFpEF. | ca_CA |
dc.format.extent | 14 p. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | MDPI | ca_CA |
dc.rights | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | ca_CA |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-sa/4.0/ | * |
dc.subject | heart failure with preserved ejection fraction | ca_CA |
dc.subject | right ventricular | ca_CA |
dc.subject | risk stratification | ca_CA |
dc.title | Right Ventricular Dysfunction Staging System for Mortality Risk Stratifiction in Heart Failure with Preserved Ejection Fraction | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | http://dx.doi.org/10.3390/jcm9030831 | |
dc.relation.projectID | the Ministry of Economy and Competitiveness, Instituto Carlos III (PI17/01426) ; CIBER Cardiovascular (16/11/00420 and 16/11/00403). | ca_CA |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | ca_CA |
dc.relation.publisherVersion | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141269/ | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |
Ficheros en el ítem
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
MED_Articles [667]
Articles de publicacions periòdiques
Excepto si se señala otra cosa, la licencia del ítem se describe como: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access
article distributed under the terms and conditions of the Creative Commons Attribution
(CC BY) license (http://creativecommons.org/licenses/by/4.0/).