Antibacterial Properties of Nanoparticles in Dental Restorative Materials. A Systematic Review and Meta-Analysis
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Other documents of the author: Ferrando-Magraner, Elena; Bellot-Arcís, Carlos; Paredes-Gallardo, Vanessa; Almerich-Silla, Jose Manuel; García-Sanz, Verónica; Fernández-Alonso, Mercedes; Montiel-Company, José María
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comunitat-uji-handle3:10234/43643
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Title
Antibacterial Properties of Nanoparticles in Dental Restorative Materials. A Systematic Review and Meta-AnalysisAuthor (s)
Date
2020Publisher
MDPIISSN
1010-660XBibliographic citation
Ferrando-Magraner, E.; Bellot-Arcís, C.; Paredes-Gallardo, V.; Almerich-Silla, J.M.; García-Sanz, V.; Fernández-Alonso, M.; Montiel-Company, J.M. Antibacterial Properties of Nanoparticles in Dental Restorative Materials. A Systematic Review and Meta-Analysis. Medicina 2020, 56, 55.Type
info:eu-repo/semantics/articlePublisher version
https://www.mdpi.com/1010-660X/56/2/55Version
info:eu-repo/semantics/publishedVersionSubject
Abstract
Background and Objectives: Nanotechnology has become a significant area of research
focused mainly on increasing the antibacterial and mechanical properties of dental materials. The aim
of the present systematic ... [+]
Background and Objectives: Nanotechnology has become a significant area of research
focused mainly on increasing the antibacterial and mechanical properties of dental materials. The aim
of the present systematic review and meta-analysis was to examine and quantitatively analyze
the current evidence for the addition of different nanoparticles into dental restorative materials,
to determine whether their incorporation increases the antibacterial/antimicrobial properties of
the materials. Materials and Methods: A literature search was performed in the Pubmed, Scopus,
and Embase databases, up to December 2018, following PRISMA (Preferred Reporting Items for
Systematic Review and Meta-Analysis) guidelines for systematic reviews and meta-analyses. Results:
A total of 624 papers were identified in the initial search. After screening the texts and applying
inclusion criteria, only 11 of these were selected for quantitative analysis. The incorporation of
nanoparticles led to a significant increase (p-value < 0.01) in the antibacterial capacity of all the
dental materials synthesized in comparison with control materials. Conclusions: The incorporation
of nanoparticles into dental restorative materials was a favorable option; the antibacterial activity
of nanoparticle-modified dental materials was significantly higher compared with the original
unmodified materials, TiO2 nanoparticles providing the greatest benefits. However, the high
heterogeneity among the articles reviewed points to the need for further research and the application
of standardized research protocols. [-]
Is part of
Medicina 2020, 56, 55Investigation project
PROMETEU/2016/079, UJI•B2016-19, FIS2016-75618-RRights
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